The presenting features of malaria in African children and Papua New Guinean adults admitted to hospital, by WHO criteria for severe falciparum malaria.*
| . | African Children† . | Nonimmune Adults‡ . |
|---|---|---|
| *The distribution of overlapping syndromes for children with severe malaria in African children and the case fatality rates are given in Figure 4. The case fatality rates for severely ill nonimmunes depend on the available supporting facilities. Adapted from Newton and Krishna, 1996. | ||
| Abbreviations: NA, not applicable. | ||
| † Marsh et al. N Engl J Med. 1995;332:1399.21 | ||
| ‡ Lalloo et al. Am J Trop Med Hyg. 1996;55:119.30 | ||
| Prevalence (%) | Prevalence (%) | |
| Defining criteria | ||
| Coma | 10.0 | 17.1 |
| Severe anemia | 17.6 | 10.0 |
| Respiratory distress | 13.7 | – |
| Hypoglycemia | 13.2 | 5.7 |
| Circulatory collapse | 0.4 | 0 |
| Renal failure | 0.1 | 22.9 |
| Spontaneous bleeding | 0.1 | 0.1 |
| Hemoglobinemia | 0.1 | 0.1 |
| Acidosis | 63.6 | NA |
| Repeated convulsions | 18.3 | 0.3 |
| Supporting criteria | ||
| Impaired consciousness | 8.2 | 37.1 |
| Jaundice | 4.7 | 45.7 |
| Prostration | 12.2 | – |
| Hyperpyrexia | 10.6 | 20 |
| Hyperparasitemia | 8.9 | 40 |
| . | African Children† . | Nonimmune Adults‡ . |
|---|---|---|
| *The distribution of overlapping syndromes for children with severe malaria in African children and the case fatality rates are given in Figure 4. The case fatality rates for severely ill nonimmunes depend on the available supporting facilities. Adapted from Newton and Krishna, 1996. | ||
| Abbreviations: NA, not applicable. | ||
| † Marsh et al. N Engl J Med. 1995;332:1399.21 | ||
| ‡ Lalloo et al. Am J Trop Med Hyg. 1996;55:119.30 | ||
| Prevalence (%) | Prevalence (%) | |
| Defining criteria | ||
| Coma | 10.0 | 17.1 |
| Severe anemia | 17.6 | 10.0 |
| Respiratory distress | 13.7 | – |
| Hypoglycemia | 13.2 | 5.7 |
| Circulatory collapse | 0.4 | 0 |
| Renal failure | 0.1 | 22.9 |
| Spontaneous bleeding | 0.1 | 0.1 |
| Hemoglobinemia | 0.1 | 0.1 |
| Acidosis | 63.6 | NA |
| Repeated convulsions | 18.3 | 0.3 |
| Supporting criteria | ||
| Impaired consciousness | 8.2 | 37.1 |
| Jaundice | 4.7 | 45.7 |
| Prostration | 12.2 | – |
| Hyperpyrexia | 10.6 | 20 |
| Hyperparasitemia | 8.9 | 40 |