Table 6.

Survival probability in relation to the expression of a set of genes included in the NF-κB cluster

Gene symbol
HR (95% CI)
P
FDR
DOS    
REL  0.42 (0.21-0.86)   .003   0.16  
TRAP1  3.20 (1.25-8.19)   .004   0.16  
ADAM17  0.41 (0.20-0.84)   .004   0.16  
TRAF5  0.51 (0.30-0.88)   .005   0.16  
FZD6  0.52 (0.30-0.89)   .005   0.16  
PFI    
PRKCA  1.80 (1.27-2.55)   .001   0.04  
ADAM17  0.44 (0.27-0.73)   .001   0.04  
CCND2  2.11 (1.30-3.43)   .001   0.04  
PAWR  0.60 (0.42-0.86)   .001   0.04  
FZD6  0.63 (0.45-0.87)   .001   0.04  
TRAP1  2.30 (1.27-4.16)   .003   0.07  
BAK1  2.12 (1.24-3.62)   .003   0.07  
HSPA8  2.45 (1.28-4.69)   .004   0.08  
MAP3K4  0.43 (0.23-0.81)   .005   0.08  
MAP4K3  0.70 (0.53-0.92)   .006   0.08  
IL2RB  1.18 (1.04-1.34)   .007   0.08  
IL 1B  1.79 (1.14-2.81)   .007   0.08  
MAP4K4  0.62 (0.43-0.89)   .008   0.09  
PRKCE  2.40 (1.17-4.93)   .008   0.09  
PIG7  2.02 (1.12-3.62)   .011   0.10  
TRAF2  2.54 (1.17-5.50)   .011   0.10  
TNFSF13  1.56 (1.08-2.27)   .012   0.10  
HCK  1.30 (1.05-1.62)   .014   0.12  
MMP17  1.93 (1.11-3.36)   .020   0.16  
MAP3K14  1.30 (1.03-1.64)   .023   0.16  
CRADD  2.48 (1.09-5.63)   .024   0.16  
PSMD2  1.68 (1.05-2.70)   .025   0.16  
PLCG2  1.50 (1.03-2.21)   .025   0.16  
STAT4  1.30 (1.02-1.65)   .026   0.16  
NFKB1E
 		 1.53 (1.02-2.29)
 		 .027
 		 0.16
 
Gene symbol
HR (95% CI)
P
FDR
DOS    
REL  0.42 (0.21-0.86)   .003   0.16  
TRAP1  3.20 (1.25-8.19)   .004   0.16  
ADAM17  0.41 (0.20-0.84)   .004   0.16  
TRAF5  0.51 (0.30-0.88)   .005   0.16  
FZD6  0.52 (0.30-0.89)   .005   0.16  
PFI    
PRKCA  1.80 (1.27-2.55)   .001   0.04  
ADAM17  0.44 (0.27-0.73)   .001   0.04  
CCND2  2.11 (1.30-3.43)   .001   0.04  
PAWR  0.60 (0.42-0.86)   .001   0.04  
FZD6  0.63 (0.45-0.87)   .001   0.04  
TRAP1  2.30 (1.27-4.16)   .003   0.07  
BAK1  2.12 (1.24-3.62)   .003   0.07  
HSPA8  2.45 (1.28-4.69)   .004   0.08  
MAP3K4  0.43 (0.23-0.81)   .005   0.08  
MAP4K3  0.70 (0.53-0.92)   .006   0.08  
IL2RB  1.18 (1.04-1.34)   .007   0.08  
IL 1B  1.79 (1.14-2.81)   .007   0.08  
MAP4K4  0.62 (0.43-0.89)   .008   0.09  
PRKCE  2.40 (1.17-4.93)   .008   0.09  
PIG7  2.02 (1.12-3.62)   .011   0.10  
TRAF2  2.54 (1.17-5.50)   .011   0.10  
TNFSF13  1.56 (1.08-2.27)   .012   0.10  
HCK  1.30 (1.05-1.62)   .014   0.12  
MMP17  1.93 (1.11-3.36)   .020   0.16  
MAP3K14  1.30 (1.03-1.64)   .023   0.16  
CRADD  2.48 (1.09-5.63)   .024   0.16  
PSMD2  1.68 (1.05-2.70)   .025   0.16  
PLCG2  1.50 (1.03-2.21)   .025   0.16  
STAT4  1.30 (1.02-1.65)   .026   0.16  
NFKB1E
 		 1.53 (1.02-2.29)
 		 .027
 		 0.16
 

Univariate Cox results for DOS and PFI. All the gene expressions have been rescaled presenting HR associated to a change of 0.25. Adjusted P values using the FDR procedure are indicated.

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