Approaches to conditioning used in for reduced intensity allogeneic stem cell transplants.
| Preparative regimen . | GVHD prophylaxis . |
|---|---|
| Table modified from Barrett & Childs12 | |
| Abbreviations: GVHD, graft-versus-host disease; ATG, antithymocyte globulin; MTX, methotrexate: MMF, mycophenolate mofetil | |
| Cyclophosphamide, fludarabine | Cyclosporine |
| Cyclophosphamide, fludarabine, ATG | Cyclosporine, ATG |
| Fludarabine, busulfan, ATG | Cyclosporine |
| Fludarabine, melphalan, | MTX, FK506 |
| Total body irradiation (200 cGy) | Cyclosporine, MMF |
| Cyclophosphamide, ATG, thymic irradiation | Cyclosporine |
| Preparative regimen . | GVHD prophylaxis . |
|---|---|
| Table modified from Barrett & Childs12 | |
| Abbreviations: GVHD, graft-versus-host disease; ATG, antithymocyte globulin; MTX, methotrexate: MMF, mycophenolate mofetil | |
| Cyclophosphamide, fludarabine | Cyclosporine |
| Cyclophosphamide, fludarabine, ATG | Cyclosporine, ATG |
| Fludarabine, busulfan, ATG | Cyclosporine |
| Fludarabine, melphalan, | MTX, FK506 |
| Total body irradiation (200 cGy) | Cyclosporine, MMF |
| Cyclophosphamide, ATG, thymic irradiation | Cyclosporine |