Table 1.

Incidence of first stroke on study (Cooperative Study of Sickle Cell Disease) by age and Hb genotype.

Age (yr.)SSSC+oTotals
* Number Per 100 Patient-Year followup; **Number of cerebrovascular accidents 
Source: Ohene-Frempong et al. Blood. 1998;91:288-294 
< 2 0.13* (1)** 0.00 0.00 0.00 0.08 (1) 
2 - 5 1.02 (20) 0.27 (2) 0.00 0.00 0.75 (22) 
6 - 9 0.79 (15) 0.00 0.00 0.00 0.55 (15) 
10 - 19 0.41 (15) 0.09 (1) 0.00 0.00 0.30 (16) 
20 - 30 0.52 (14) 0.16 (1) 0.46 (1) 0.43 (1) 0.45 (17) 
30 - 39 0.59 (8) 0.00 0.00 0.00 0.39 (8) 
40 - 49 0.74 (3) 1.01 (2) 0.00 0.00 0.76 (5) 
50 - 1.28 (2) 0.76 (1) 0.00 0.00 0.91 (3 
OVERALL 0.61 (78) 0.17 (7) 0.11 (1) 0.10 (1) 0.46 (87) 
Age-adjusted 0.61 0.15 0.09 0.08  
Age (yr.)SSSC+oTotals
* Number Per 100 Patient-Year followup; **Number of cerebrovascular accidents 
Source: Ohene-Frempong et al. Blood. 1998;91:288-294 
< 2 0.13* (1)** 0.00 0.00 0.00 0.08 (1) 
2 - 5 1.02 (20) 0.27 (2) 0.00 0.00 0.75 (22) 
6 - 9 0.79 (15) 0.00 0.00 0.00 0.55 (15) 
10 - 19 0.41 (15) 0.09 (1) 0.00 0.00 0.30 (16) 
20 - 30 0.52 (14) 0.16 (1) 0.46 (1) 0.43 (1) 0.45 (17) 
30 - 39 0.59 (8) 0.00 0.00 0.00 0.39 (8) 
40 - 49 0.74 (3) 1.01 (2) 0.00 0.00 0.76 (5) 
50 - 1.28 (2) 0.76 (1) 0.00 0.00 0.91 (3 
OVERALL 0.61 (78) 0.17 (7) 0.11 (1) 0.10 (1) 0.46 (87) 
Age-adjusted 0.61 0.15 0.09 0.08  
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