Liver transduction with FIV constructs
. | . | Transduced cell type, % . | . | |
|---|---|---|---|---|
| Vector . | % Transduction* . | Hepatocytes . | Nonhepatocytes . | |
| GP64/CMV-βgal; n = 8 | 15.2 (1.4) | 98 | 2 | |
| GP64/AlbE/AAT-βgal; n = 3 | 23.4 (2.6) | 99.4 | 0.6 | |
| RRV/FIV-RSV-cyto-β-gal; best34 | 6 | 75 | 25 | |
| VSV-G/FIV-RSV-cyto-β-gal; best34 | 3 | 75 | 25 | |
. | . | Transduced cell type, % . | . | |
|---|---|---|---|---|
| Vector . | % Transduction* . | Hepatocytes . | Nonhepatocytes . | |
| GP64/CMV-βgal; n = 8 | 15.2 (1.4) | 98 | 2 | |
| GP64/AlbE/AAT-βgal; n = 3 | 23.4 (2.6) | 99.4 | 0.6 | |
| RRV/FIV-RSV-cyto-β-gal; best34 | 6 | 75 | 25 | |
| VSV-G/FIV-RSV-cyto-β-gal; best34 | 3 | 75 | 25 | |
All mice received similar doses of vector (1 × 108 to 3.5 × 108 TU).
Best indicates highest expression levels achieved.
Mean (± SE).