Differences between intravenous gammaglobulin (IVIG) and intravenous anti-D (IV anti-D) in immune thrombocytopenic purpura.
| . | IVIG . | IV anti-D . |
|---|---|---|
| Abbreviations: IVIG, intravenous gammaglobulin; HIV, human immundeficiency virus | ||
| 1. platelet responses in Rh- patients: | + | - |
| 2. platelet responses in splenectomized pts: | + | - |
| 3. rate of plt increase: 1 gm/kg & 50 mcg/kg: (24 hr) | fast (72 hr) | slow |
| 4. relative effect in HIV+ patients | - | + |
| 5. duration of plt incr related to acute plt incr | no | yes |
| 6. Fc receptor involved in acute effect | ?II | ?III |
| . | IVIG . | IV anti-D . |
|---|---|---|
| Abbreviations: IVIG, intravenous gammaglobulin; HIV, human immundeficiency virus | ||
| 1. platelet responses in Rh- patients: | + | - |
| 2. platelet responses in splenectomized pts: | + | - |
| 3. rate of plt increase: 1 gm/kg & 50 mcg/kg: (24 hr) | fast (72 hr) | slow |
| 4. relative effect in HIV+ patients | - | + |
| 5. duration of plt incr related to acute plt incr | no | yes |
| 6. Fc receptor involved in acute effect | ?II | ?III |