Properties of BCL-2.
| •Oncogenic protein |
| •Anti-apoptotic |
| •Mitochondrial, endoplasmic reticulum, nuclear membrane localizations |
| •Homotypic and heterotypic dimerization within family |
| •Membrane channel/pore function |
| •Cytochrome C release from mitochondria via BCL-2 family channels regulates cell fate under stress |
| •Oncogenic protein |
| •Anti-apoptotic |
| •Mitochondrial, endoplasmic reticulum, nuclear membrane localizations |
| •Homotypic and heterotypic dimerization within family |
| •Membrane channel/pore function |
| •Cytochrome C release from mitochondria via BCL-2 family channels regulates cell fate under stress |