Function of the germinal center reaction.
| • Generation of memory B cells and plasma cells. |
| • Affinity maturation of the Ig receptors by somatic hypermutation and antigen selection. |
| • Increase of the defence efficiency of the secreted Ig (antibodies) by changing their effector domains by means of isotype switch. |
| • Generation of memory B cells and plasma cells. |
| • Affinity maturation of the Ig receptors by somatic hypermutation and antigen selection. |
| • Increase of the defence efficiency of the secreted Ig (antibodies) by changing their effector domains by means of isotype switch. |