Table 5.

Relapse following allogeneic transplant, autologous transplant and chemotherapy.

Allogeneic transplantAutologous transplantChemoStudy therapy
* Data for children excluded. In the MRC study, BMT was compared with an observation arm after 4 cycles of chemotherapy, rather than a direct comparison with high-dose chemotherapy as in the other studies. 
Abbreviations: See Table 3; GIMEMA, Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto 
GIMEMA, 199528  24% 40% 57% 
GOELAM, 199724  28% 45% 55% 
*MRC, 199825  19% 35% 53% 
ECOG/SWOG, 199826  29% 48% 61% 
Allogeneic transplantAutologous transplantChemoStudy therapy
* Data for children excluded. In the MRC study, BMT was compared with an observation arm after 4 cycles of chemotherapy, rather than a direct comparison with high-dose chemotherapy as in the other studies. 
Abbreviations: See Table 3; GIMEMA, Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto 
GIMEMA, 199528  24% 40% 57% 
GOELAM, 199724  28% 45% 55% 
*MRC, 199825  19% 35% 53% 
ECOG/SWOG, 199826  29% 48% 61% 
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