Cytogenetic classification.
. | SWOG Criteria27 . | MRC criteria2: As for SWOG, except: - . |
---|---|---|
Abbreviations: SWOG, Southwestern Oncology Group; MRC, Medical Research Council; abn, abnormalities of | ||
Favorable | t(15;17) – with any other abnormality | |
inv(16)/t(16;16)/del(16q) – with any other abnormality | ||
t(8;21) – without del(9q) or complex karyotype | t(8;21) – with any other abnormality | |
Intermediate | +8, -Y, +6, del(12p) | abn 11q23 |
normal karyotype | del(9q), del(7q) – without other abnormalities | |
Complex karyotypes (≥ 3 abnormalities, but < 5 abnormalities) | ||
All abnormalities of unknown prognostic significance | ||
Unfavorable | -5/del(5q), -7/del(7q), | |
t(8;21) with del(9q) or complex karyotype | ||
inv(3q), abn 11q23, 20q, | ||
21q, del(9q), t(6;9) | ||
t(9;22), abn 17p, | ||
Complex karyotypes (≥ 3 abnormalities) | Complex karyotypes (≥ 5 abnormalities) | |
Unknown | All other clonal chromosomal aberrations with fewer than 3 abnormalities |
. | SWOG Criteria27 . | MRC criteria2: As for SWOG, except: - . |
---|---|---|
Abbreviations: SWOG, Southwestern Oncology Group; MRC, Medical Research Council; abn, abnormalities of | ||
Favorable | t(15;17) – with any other abnormality | |
inv(16)/t(16;16)/del(16q) – with any other abnormality | ||
t(8;21) – without del(9q) or complex karyotype | t(8;21) – with any other abnormality | |
Intermediate | +8, -Y, +6, del(12p) | abn 11q23 |
normal karyotype | del(9q), del(7q) – without other abnormalities | |
Complex karyotypes (≥ 3 abnormalities, but < 5 abnormalities) | ||
All abnormalities of unknown prognostic significance | ||
Unfavorable | -5/del(5q), -7/del(7q), | |
t(8;21) with del(9q) or complex karyotype | ||
inv(3q), abn 11q23, 20q, | ||
21q, del(9q), t(6;9) | ||
t(9;22), abn 17p, | ||
Complex karyotypes (≥ 3 abnormalities) | Complex karyotypes (≥ 5 abnormalities) | |
Unknown | All other clonal chromosomal aberrations with fewer than 3 abnormalities |