Table 5.

Clinical features useful in distinguishing primary cutaneous anaplastic large cell lymphoma (ALCL) and lymphomatoid papulosis (LyP).

Clinical FeaturesLyPALCL
* > 3 cm more predictive of lymphoma; borderline lesions are usually intermediate in size, 1-2 cm. 
Modified from Kinney and Kadin, 1999 42  
Type of lesion Papules, nodules Nodules, tumors 
Number Multiple Single or grouped 
Size Usually <1 cm* > 2 cm* 
Sites of disease Extremities, trunk Extremities, head and neck 
Regression Yes, usually with a scar ∼25% of cases 
Clinical FeaturesLyPALCL
* > 3 cm more predictive of lymphoma; borderline lesions are usually intermediate in size, 1-2 cm. 
Modified from Kinney and Kadin, 1999 42  
Type of lesion Papules, nodules Nodules, tumors 
Number Multiple Single or grouped 
Size Usually <1 cm* > 2 cm* 
Sites of disease Extremities, trunk Extremities, head and neck 
Regression Yes, usually with a scar ∼25% of cases 
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