Table 4.

ALKgene dysregulation and the classification of anaplastic large cell lymphoma (ALCL).

Abbreviations: SCV, small cell variant; EMA, epithelial membrane antigen; LyP, lymphomatoid papulosis; MF, mycosis fungoides; HD, Hodgkin's disease; HIV, human immunodeficiency virus 
ALK-positive Group 
Distinct clinicopathologic entity: 
    •young patients 
    •systemic disease 
    •variable histology (ALCL → SCV) 
    •T or null cell, EMA+ 
ALK-negative Group 
Heterogeneous group of lymphomas: 
    •primary cutaneous 
    •Hodgkin's related 
    •Secondary ALCL in patients with LyP, MF, HD 
    •CD30+ large B-cell lymphomas 
    •ALCL in HIV+ patients 
Abbreviations: SCV, small cell variant; EMA, epithelial membrane antigen; LyP, lymphomatoid papulosis; MF, mycosis fungoides; HD, Hodgkin's disease; HIV, human immunodeficiency virus 
ALK-positive Group 
Distinct clinicopathologic entity: 
    •young patients 
    •systemic disease 
    •variable histology (ALCL → SCV) 
    •T or null cell, EMA+ 
ALK-negative Group 
Heterogeneous group of lymphomas: 
    •primary cutaneous 
    •Hodgkin's related 
    •Secondary ALCL in patients with LyP, MF, HD 
    •CD30+ large B-cell lymphomas 
    •ALCL in HIV+ patients 
Close Modal

or Create an Account

Close Modal
Close Modal