Post-thymic T and NK cell neoplasms in the WHO and REAL classifications.
| * originally described as aggressive NK cell leukemia/lymphoma |
| ** Adult T-cell leukemia/lymphoma (ATLL) has varied clinical presentations that can be predominantly leukemic or lymphomatous Abbreviastions: HTLV, human T-cell lymphotrophic virus; AILD, angioimmunoblastic lymphadenopathy |
| Predominantly Leukemic Malignancies |
| T-cell prolymphocytic leukemia |
| T-cell granular lymphocytic leukemia |
| Aggressive NK-cell leukemia* |
| Adult T-cell lymphoma/leukemia (HTLV-1+)** |
| Predominantly Lymphoma |
| Peripheral T-cell lymphoma, unspecified |
| Angioimmunoblastic T-cell lymphoma (AILD-like) |
| Adult T-cell leukemia/lymphoma (HTLV-1+)** |
| Anaplastic large cell lymphoma (T- and null cell) |
| Predominantly Extranodal Malignancies |
| Indolent: |
| Mycosis fungoides/Sézary syndrome |
| Primary cutaneous anaplastic large cell lymphoma |
| Aggressive: |
| Extranodal NK/T cell lymphoma, nasal and nasal type |
| Blastic NK cell lymphoma |
| Enteropathy-type T-cell lymphoma |
| Subcutaneous panniculitis-like T-cell lymphoma |
| Hepatosplenic T-cell lymphoma |
| * originally described as aggressive NK cell leukemia/lymphoma |
| ** Adult T-cell leukemia/lymphoma (ATLL) has varied clinical presentations that can be predominantly leukemic or lymphomatous Abbreviastions: HTLV, human T-cell lymphotrophic virus; AILD, angioimmunoblastic lymphadenopathy |
| Predominantly Leukemic Malignancies |
| T-cell prolymphocytic leukemia |
| T-cell granular lymphocytic leukemia |
| Aggressive NK-cell leukemia* |
| Adult T-cell lymphoma/leukemia (HTLV-1+)** |
| Predominantly Lymphoma |
| Peripheral T-cell lymphoma, unspecified |
| Angioimmunoblastic T-cell lymphoma (AILD-like) |
| Adult T-cell leukemia/lymphoma (HTLV-1+)** |
| Anaplastic large cell lymphoma (T- and null cell) |
| Predominantly Extranodal Malignancies |
| Indolent: |
| Mycosis fungoides/Sézary syndrome |
| Primary cutaneous anaplastic large cell lymphoma |
| Aggressive: |
| Extranodal NK/T cell lymphoma, nasal and nasal type |
| Blastic NK cell lymphoma |
| Enteropathy-type T-cell lymphoma |
| Subcutaneous panniculitis-like T-cell lymphoma |
| Hepatosplenic T-cell lymphoma |