Factors contributing to anemia in patients with P. falciparum malaria.
| Factor . | References . |
|---|---|
| Destruction of parasitized red blood cells. | 2,5,6,17,18,19,20 |
| Destruction of non-parasitized red blood cells by immune and non-immune factors | 21,22,23,24 |
| Splenic sequestration of red blood cells | 21,25,26 |
| Bone marrow suppression | 5,12 |
| Ineffective erythropoiesis and dyserythropoiesis | 4, 8,9,14,19 |
| Inadequate erythropoietin production | 15,16 |
| Pre-morbid nutritional abnormalities such as deficiencies of folic acid or iron | 5 |
| Concomitant parasitic and bacterial infections | 5 |
| Factor . | References . |
|---|---|
| Destruction of parasitized red blood cells. | 2,5,6,17,18,19,20 |
| Destruction of non-parasitized red blood cells by immune and non-immune factors | 21,22,23,24 |
| Splenic sequestration of red blood cells | 21,25,26 |
| Bone marrow suppression | 5,12 |
| Ineffective erythropoiesis and dyserythropoiesis | 4, 8,9,14,19 |
| Inadequate erythropoietin production | 15,16 |
| Pre-morbid nutritional abnormalities such as deficiencies of folic acid or iron | 5 |
| Concomitant parasitic and bacterial infections | 5 |