Direct recognition and lysis of leukemia cells by NIK-1: experiment 4
. | Colony formation . | . | |
|---|---|---|---|
| Donor . | CFU-GM . | BFU-E . | |
| HLA-DP5-positive donor no. 1 | |||
| Without NIK-1 | 56 ± 5 | 86 ± 8 | |
| With NIK-1 | 59 ± 7 | 93 ± 10 | |
| With NIK-1 and WT1 peptide | 29 ± 3 | 37 ± 7 | |
| HLA-DP5-positive donor no. 2 | |||
| Without NIK-1 | 136 ± 14 | 167 ± 24 | |
| With NIK-1 | 138 ± 8 | 170 ± 23 | |
| With NIK-1 and WT1 peptide | 66 ± 14 | 62 ± 13 | |
| HLA-DP5-negative donor no. 3 | |||
| Without NIK-1 | 86 ± 15 | 96 ± 18 | |
| With NIK-1 | 88 ± 7 | 100 ± 10 | |
| With NIK-1 and WT1 peptide | 85 ± 15 | 103 ± 8 | |
. | Colony formation . | . | |
|---|---|---|---|
| Donor . | CFU-GM . | BFU-E . | |
| HLA-DP5-positive donor no. 1 | |||
| Without NIK-1 | 56 ± 5 | 86 ± 8 | |
| With NIK-1 | 59 ± 7 | 93 ± 10 | |
| With NIK-1 and WT1 peptide | 29 ± 3 | 37 ± 7 | |
| HLA-DP5-positive donor no. 2 | |||
| Without NIK-1 | 136 ± 14 | 167 ± 24 | |
| With NIK-1 | 138 ± 8 | 170 ± 23 | |
| With NIK-1 and WT1 peptide | 66 ± 14 | 62 ± 13 | |
| HLA-DP5-negative donor no. 3 | |||
| Without NIK-1 | 86 ± 15 | 96 ± 18 | |
| With NIK-1 | 88 ± 7 | 100 ± 10 | |
| With NIK-1 and WT1 peptide | 85 ± 15 | 103 ± 8 | |
The colony formation by normal bone marrow cells cocultured with or without NIK-1 cells in the presence or absence of WT1 peptide.