Prediction confusion matrix for 13 subtypes as determined by resampling using SVM
. | Real . | . | . | . | . | . | . | . | . | . | . | . | . | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Confusion matrix . | c-ALL/Pre-B-ALL . | Pro-B-ALL with t(11q23) . | Mature B-ALL with t(8;14) . | T-ALL . | AML with t(15;17) . | AML with t(8;21) . | AML with inv(16) . | AML with t(11q23) . | AML with complex karyotype . | AML normal/other . | CLL . | CML . | Nonleukemia . | ||||||||||||
| c-ALL/Pre-B-ALL | 25.77 | 0.02 | 0.85 | — | — | — | — | — | — | 0.27 | — | 0.07 | 0.14 | ||||||||||||
| Pro-B-ALL with t(11q23) | — | 8.54 | — | — | — | — | — | — | — | — | — | — | — | ||||||||||||
| Mature B-ALL with t(8;14) | 0.15 | — | 2.57 | — | — | — | — | — | — | 0.11 | 0.02 | — | 0.04 | ||||||||||||
| T-ALL | — | — | — | 9.23 | — | — | — | — | 0.36 | 0.04 | — | — | — | ||||||||||||
| AML with t(15;17) | — | — | — | — | 14 | — | — | — | — | — | — | — | — | ||||||||||||
| AML with t(8;21) | — | — | — | — | — | 11.43 | 0.04 | — | — | — | — | — | — | ||||||||||||
| AML with inv(16) | — | — | — | — | — | — | 15.7 | — | — | — | — | — | — | ||||||||||||
| AML with t(11q23) | — | — | — | — | — | — | — | 13.05 | 0.01 | 1.23 | — | — | 0.04 | ||||||||||||
| AML with complex karyotype | — | — | — | — | — | 0.11 | — | — | 21.38 | 1.36 | — | 0.02 | 0.09 | ||||||||||||
| AML normal/other | 1.43 | 0.44 | 0.36 | 0.77 | — | 0.46 | 0.26 | 2.71 | 3.14 | 119.1 | 0.36 | 0.80 | 1.02 | ||||||||||||
| CLL | — | — | — | — | — | — | — | — | — | — | 14.62 | — | — | ||||||||||||
| CML | 0.09 | — | — | — | — | — | — | 0.18 | — | 0.48 | — | 23.82 | 0.44 | ||||||||||||
| Nonleukemia | 0.56 | — | 0.22 | — | — | — | — | 0.06 | 0.11 | 0.41 | — | 0.29 | 13.23 | ||||||||||||
| Total (n = 312) | 28 | 9 | 4 | 10 | 14 | 12 | 16 | 16 | 25 | 123 | 15 | 25 | 15 | ||||||||||||
. | Real . | . | . | . | . | . | . | . | . | . | . | . | . | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Confusion matrix . | c-ALL/Pre-B-ALL . | Pro-B-ALL with t(11q23) . | Mature B-ALL with t(8;14) . | T-ALL . | AML with t(15;17) . | AML with t(8;21) . | AML with inv(16) . | AML with t(11q23) . | AML with complex karyotype . | AML normal/other . | CLL . | CML . | Nonleukemia . | ||||||||||||
| c-ALL/Pre-B-ALL | 25.77 | 0.02 | 0.85 | — | — | — | — | — | — | 0.27 | — | 0.07 | 0.14 | ||||||||||||
| Pro-B-ALL with t(11q23) | — | 8.54 | — | — | — | — | — | — | — | — | — | — | — | ||||||||||||
| Mature B-ALL with t(8;14) | 0.15 | — | 2.57 | — | — | — | — | — | — | 0.11 | 0.02 | — | 0.04 | ||||||||||||
| T-ALL | — | — | — | 9.23 | — | — | — | — | 0.36 | 0.04 | — | — | — | ||||||||||||
| AML with t(15;17) | — | — | — | — | 14 | — | — | — | — | — | — | — | — | ||||||||||||
| AML with t(8;21) | — | — | — | — | — | 11.43 | 0.04 | — | — | — | — | — | — | ||||||||||||
| AML with inv(16) | — | — | — | — | — | — | 15.7 | — | — | — | — | — | — | ||||||||||||
| AML with t(11q23) | — | — | — | — | — | — | — | 13.05 | 0.01 | 1.23 | — | — | 0.04 | ||||||||||||
| AML with complex karyotype | — | — | — | — | — | 0.11 | — | — | 21.38 | 1.36 | — | 0.02 | 0.09 | ||||||||||||
| AML normal/other | 1.43 | 0.44 | 0.36 | 0.77 | — | 0.46 | 0.26 | 2.71 | 3.14 | 119.1 | 0.36 | 0.80 | 1.02 | ||||||||||||
| CLL | — | — | — | — | — | — | — | — | — | — | 14.62 | — | — | ||||||||||||
| CML | 0.09 | — | — | — | — | — | — | 0.18 | — | 0.48 | — | 23.82 | 0.44 | ||||||||||||
| Nonleukemia | 0.56 | — | 0.22 | — | — | — | — | 0.06 | 0.11 | 0.41 | — | 0.29 | 13.23 | ||||||||||||
| Total (n = 312) | 28 | 9 | 4 | 10 | 14 | 12 | 16 | 16 | 25 | 123 | 15 | 25 | 15 | ||||||||||||
Matrix shows the predicted class as determined after 100 runs of SVM-based classifications. Average numbers of predictions per run are given. The total data set (N = 937) was randomly separated into a training set (n = 625) and a test set (n = 312) for each of the 100 runs. Data given are the average numbers of respective classification.
- indicates no case.