Table 4. Event-free survival rates in... | American Society of Hematology

Table 4.

Event-free survival rates in infant ALL.

Trial	Event-Free Survival	Reference
CCG 107	33% EFS @ 4 yrs	Reaman²
CCG 1883	39% EFS @ 4 yrs
	3% t(4;11)^*
	50% other 11q23^*
	49% normal karyotype^*	Reaman⁸
POG 8493	28% EFS @ 4 yrs
	57% > 9 mos old @ diagnosis
	18% < 9 mos old @ diagnosis	Frankel³
BFM 83, 86, 90	43% pEFS @ 6 yrs
	53% Prednisone good response
	15% Prednisone poor response	Dordelmann⁷
CLCG-EORTC 58881	41% EFS @ 4 yrs	Ferster⁵
UK ALL VIII, X, pilot	24% @ 6 yrs
	40% > 6 mos old @ diagnosis
	10% < 6 mos old @ diagnosis	Chessells⁴
Total Therapy X-XIII	EFS @ 5 yrs
	56% (-)11q23/MLL rearrangements
	6% (+)11q23/MLL rearrangements
	42% > 6 mos old @ diagnosis
	8% < 6 mos old @ diagnosis	Pui⁶
Dana Farber Consortium	54% DFS @ 50 mos	Silverman⁴⁴

Trial	Event-Free Survival	Reference
CCG 107	33% EFS @ 4 yrs	Reaman²
CCG 1883	39% EFS @ 4 yrs
	3% t(4;11)^*
	50% other 11q23^*
	49% normal karyotype^*	Reaman⁸
POG 8493	28% EFS @ 4 yrs
	57% > 9 mos old @ diagnosis
	18% < 9 mos old @ diagnosis	Frankel³
BFM 83, 86, 90	43% pEFS @ 6 yrs
	53% Prednisone good response
	15% Prednisone poor response	Dordelmann⁷
CLCG-EORTC 58881	41% EFS @ 4 yrs	Ferster⁵
UK ALL VIII, X, pilot	24% @ 6 yrs
	40% > 6 mos old @ diagnosis
	10% < 6 mos old @ diagnosis	Chessells⁴
Total Therapy X-XIII	EFS @ 5 yrs
	56% (-)11q23/MLL rearrangements
	6% (+)11q23/MLL rearrangements
	42% > 6 mos old @ diagnosis
	8% < 6 mos old @ diagnosis	Pui⁶
Dana Farber Consortium	54% DFS @ 50 mos	Silverman⁴⁴

includes CCG 107; Abbreviations: EFS, event-free survival; DFS, disease-free survival; CCG Children's Cancer Group; POG, Pediatric Oncology Group; BFM, Berlin-Frankfurt-Münster; CLCG-EORTC, Children's Leukemia Cooperative Group of the European Oncology Research and Treatment Cooperative

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