Variables that affect outcomes of unrelated donor transplants in chronic myelogenous leukemia (CML).
. | Outcome . | |
---|---|---|
Variable (Reference) . | GVHD . | Survival . |
Chronic phase status at time of SCT (59,62) | - | + |
Serologic mismatch Class I or II (59,61,65) | + | 0 |
Molecular mismatch (62,66,67) | + | - |
Older age (59,62) | 0 | - |
Transplant < 12 months from diagnosis (59,62) | 0 | + |
CMV positivity (59,61) | 0 | - |
T-cell depletion (59) | - | 0 |
Abbreviations: GVHD, graft-versus-host disease; -, negative effect; +, positive effect; 0, no significant effect |
. | Outcome . | |
---|---|---|
Variable (Reference) . | GVHD . | Survival . |
Chronic phase status at time of SCT (59,62) | - | + |
Serologic mismatch Class I or II (59,61,65) | + | 0 |
Molecular mismatch (62,66,67) | + | - |
Older age (59,62) | 0 | - |
Transplant < 12 months from diagnosis (59,62) | 0 | + |
CMV positivity (59,61) | 0 | - |
T-cell depletion (59) | - | 0 |
Abbreviations: GVHD, graft-versus-host disease; -, negative effect; +, positive effect; 0, no significant effect |