Proposed risk classification for allogeneic stem cell transplantation (SCT).55
| Risk factors are donor type (0 for HLA-identical sibling donor, 1 for a matched unrelated donor); disease stage (0 for first chronic phase, 1 for accelerated phase, and 2 for blast crisis or higher chronic phase); age of recipient (0 for < 20 years, 1 for 20-40 years, and 2 for > 40 years); sex combination (0 for all, except 1 for male recipient/female donor); and time from diagnosis to SCT (0 for < 12 months, 1 for > 12 months) | |||
| Results at 5 years | |||
| Risk Factors | % of Patients with Risk Factors | Leukemia-Free Survival (%) | Transplant-Related Mortality (%) |
| 0 | 2 | 60 | 20 |
| 1 | 18 | 60 | 23 |
| 2 | 28 | 47 | 31 |
| 3 | 28 | 37 | 46 |
| 4 | 15 | 35 | 51 |
| 5 | 7 | 19 | 71 |
| 6-7 | 2 | 16 | 73 |
| Adapted from Gratwohl et al.55 | |||
| Risk factors are donor type (0 for HLA-identical sibling donor, 1 for a matched unrelated donor); disease stage (0 for first chronic phase, 1 for accelerated phase, and 2 for blast crisis or higher chronic phase); age of recipient (0 for < 20 years, 1 for 20-40 years, and 2 for > 40 years); sex combination (0 for all, except 1 for male recipient/female donor); and time from diagnosis to SCT (0 for < 12 months, 1 for > 12 months) | |||
| Results at 5 years | |||
| Risk Factors | % of Patients with Risk Factors | Leukemia-Free Survival (%) | Transplant-Related Mortality (%) |
| 0 | 2 | 60 | 20 |
| 1 | 18 | 60 | 23 |
| 2 | 28 | 47 | 31 |
| 3 | 28 | 37 | 46 |
| 4 | 15 | 35 | 51 |
| 5 | 7 | 19 | 71 |
| 6-7 | 2 | 16 | 73 |
| Adapted from Gratwohl et al.55 | |||