Table 7.

Risks for secondary cancers after Hodgkin's disease.

Tumor Site
Observed/Expected
Relative Risk
95% Confidence Intervals
Absolute Risk*
All cancers-Incidence  197 / 30.8   6.4   5.5 - 7.3   84.4  
Leukemia  38 / 1.0   37.7   25.7 - 49.7   18.4  
Acute myelogenous leukemia   35 / 0.24   144.1   96.4 - 191.9   17.3  
Non-Hodgkin's lymphoma   33 / 0.9   35.3   23.2 - 47.3   16.0  
All solid tumors   126 / 29.4   4.3   3.5 - 5.0   48.8  
All cancers-Mortality   104 / 16.6   6.3   5.1 - 7.5   43.5  
Tumor Site
Observed/Expected
Relative Risk
95% Confidence Intervals
Absolute Risk*
All cancers-Incidence  197 / 30.8   6.4   5.5 - 7.3   84.4  
Leukemia  38 / 1.0   37.7   25.7 - 49.7   18.4  
Acute myelogenous leukemia   35 / 0.24   144.1   96.4 - 191.9   17.3  
Non-Hodgkin's lymphoma   33 / 0.9   35.3   23.2 - 47.3   16.0  
All solid tumors   126 / 29.4   4.3   3.5 - 5.0   48.8  
All cancers-Mortality   104 / 16.6   6.3   5.1 - 7.5   43.5  
*

Absolute risk is the excess number of observed cancers (or deaths) per 10,000 patients per year according to the formula: Absolute risk = [(observed - expected) / person-years] × 10,000.

Risks for all cancers and for leukemia or myelogenous leukemia exclude 3 cases of myelodysplastic syndrome because this disease is excluded from the general population rates published by S.E.E.R., which was used for these relative risk calculations.

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