Theoretical and applied methods of safeguarding future fertility in patients undergoing high-dose cytotoxic treatment.
| Procedure . | Male . | Female . | 
|---|---|---|
| Ligand-receptor mediated | GnRHa | GnRHa, steroids | 
| Inhibition of apoptosis | - | Bax | 
| Surgical | - | Ovarian transposition | 
| Cryopreservation | Sperm, spermatogonia | Embryos, oocytes, primordial follicles | 
| Abbreviation: GnRHa, gonadotropin-releasing hormone agonists | ||
| Procedure . | Male . | Female . | 
|---|---|---|
| Ligand-receptor mediated | GnRHa | GnRHa, steroids | 
| Inhibition of apoptosis | - | Bax | 
| Surgical | - | Ovarian transposition | 
| Cryopreservation | Sperm, spermatogonia | Embryos, oocytes, primordial follicles | 
| Abbreviation: GnRHa, gonadotropin-releasing hormone agonists | ||