Human albumin- or CK19-expressing cell numbers in the sections from AA-treated rat liver injected with hMSCs
Time after transplantation, d . | No. positive cells at equator, mean ± SD . | . | No. positive cells in nodule, mean ± SD . | . | hAlb+ or CK19+ cells/injected hMSCs, %*, mean ± SD . | . | |||
|---|---|---|---|---|---|---|---|---|---|
| . | Albumin . | CK19 . | Albumin . | CK19 . | Albumin . | CK19 . | |||
| 14 | 50 ± 24 | 52 ± 18 | 354 ± 205 | 375 ± 211 | 0.035 ± 0.02 | 0.038 ± 0.021 | |||
| 28 | 292 ± 51 | 7 ± 3 | 4990 ± 1362 | ND | 0.49 ± 0.136 | ND | |||
| 56 | 29 ± 11 | 0 ± 0 | 156 ± 97 | ND | 0.016 ± 0.01 | ND | |||
Time after transplantation, d . | No. positive cells at equator, mean ± SD . | . | No. positive cells in nodule, mean ± SD . | . | hAlb+ or CK19+ cells/injected hMSCs, %*, mean ± SD . | . | |||
|---|---|---|---|---|---|---|---|---|---|
| . | Albumin . | CK19 . | Albumin . | CK19 . | Albumin . | CK19 . | |||
| 14 | 50 ± 24 | 52 ± 18 | 354 ± 205 | 375 ± 211 | 0.035 ± 0.02 | 0.038 ± 0.021 | |||
| 28 | 292 ± 51 | 7 ± 3 | 4990 ± 1362 | ND | 0.49 ± 0.136 | ND | |||
| 56 | 29 ± 11 | 0 ± 0 | 156 ± 97 | ND | 0.016 ± 0.01 | ND | |||
Data shown are from 4 rats from 2 experiments. ND indicates not done; the number of CK19+ cells was not tested since they did not form apparent nodules. hAlb indicates human albumin.
Differentiation efficiency is expressed by dividing the total number of hALb- or CK19-expressing cells by the number of injected hMSCs.