FISH analysis for hMSC-derived hepatocytes in rat liver
Rat . | No. total nuclei . | No. FISH signal+ nuclei (% of total nuclei) . | No. human FISH+ nuclei (% of FISH+ total nuclei) . | No. rat FISH+ nuclei (% of total FISH+ nuclei) . | No. human and rat FISH+ nuclei (% of total FISH+ nuclei) . | No. albumin+ cells . | No. human FISH+ nuclei (% of albumin+ cells) . | No. rat FISH+ nuclei (% of albumin+ cells) . |
|---|---|---|---|---|---|---|---|---|
| No. 1 | 480 | 228 (47.5) | 122 (53.5) | 106 (46.5) | 0 (0.0) | 200 | 122 (61.0) | 0 (0.0) |
| No. 2 | 600 | 360 (60.0) | 220 (61.1) | 140 (38.9) | 0 (0.0) | 240 | 220 (91.7) | 0 (0.0) |
| No. 3 | 360 | 252 (70.0) | 168 (66.7) | 84 (33.3) | 0 (0.0) | 76 | 76 (100.0) | 0 (0.0) |
| Total | 1440 | 840 (58.3) | 510 (60.7) | 330 (39.3) | 0 (0.0) | 516 | 418 (81.0) | 0 (0.0) |
Rat . | No. total nuclei . | No. FISH signal+ nuclei (% of total nuclei) . | No. human FISH+ nuclei (% of FISH+ total nuclei) . | No. rat FISH+ nuclei (% of total FISH+ nuclei) . | No. human and rat FISH+ nuclei (% of total FISH+ nuclei) . | No. albumin+ cells . | No. human FISH+ nuclei (% of albumin+ cells) . | No. rat FISH+ nuclei (% of albumin+ cells) . |
|---|---|---|---|---|---|---|---|---|
| No. 1 | 480 | 228 (47.5) | 122 (53.5) | 106 (46.5) | 0 (0.0) | 200 | 122 (61.0) | 0 (0.0) |
| No. 2 | 600 | 360 (60.0) | 220 (61.1) | 140 (38.9) | 0 (0.0) | 240 | 220 (91.7) | 0 (0.0) |
| No. 3 | 360 | 252 (70.0) | 168 (66.7) | 84 (33.3) | 0 (0.0) | 76 | 76 (100.0) | 0 (0.0) |
| Total | 1440 | 840 (58.3) | 510 (60.7) | 330 (39.3) | 0 (0.0) | 516 | 418 (81.0) | 0 (0.0) |
Data are derived from 3 different livers from day-28 rats that underwent hMSC transplantatin and treatment with multiple AA.