Table 1.

The relative ES cell contribution to the indicated tissues in chimeric mice


Injected ES cells and mouse no.

% ES contribution in toe tissue

% ES contribution in myeloid CFCs (no. B-raf-/- colonies/total no. colonies assayed)

% ES contribution in megakaryocytes (% contribution relative to myeloid CFCs)
B-raf-/-    
    1   23.1   25.0 (16/64)   6.4 (25.6)  
    2   25.9   35.8 (19/53)   NA  
    8   61.1   86.7 (39/45)   32.7 (37.7)  
    9   31.4   2.1 (1/47)   0.2 (9.5)  
B-raf-/-    
    3
 
6.4
 
13.6 (6/44)
 
8.7 (64.0)
 

Injected ES cells and mouse no.

% ES contribution in toe tissue

% ES contribution in myeloid CFCs (no. B-raf-/- colonies/total no. colonies assayed)

% ES contribution in megakaryocytes (% contribution relative to myeloid CFCs)
B-raf-/-    
    1   23.1   25.0 (16/64)   6.4 (25.6)  
    2   25.9   35.8 (19/53)   NA  
    8   61.1   86.7 (39/45)   32.7 (37.7)  
    9   31.4   2.1 (1/47)   0.2 (9.5)  
B-raf-/-    
    3
 
6.4
 
13.6 (6/44)
 
8.7 (64.0)
 

CFCs indicates colony-forming cells; NA, not applicable.

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