Spleen weights of pIpC-treated mice
Genotype . | No. mice . | Days after pIpC . | Spleen weight, mg, mean ± SD . | Fold increase . |
|---|---|---|---|---|
| Runx1F/F | 7 | 60-273 | 153 ± 48 | — |
| Runx1F/F—Tg(Mx1-Cre) | 9 | 91-273 | 318‡ ± 195 | 2.08 |
| Runx1F/+ | 4 | 154 | 122 ± 26 | — |
| Runx1F/rd and Runx1F/+—Tg(Mx1-Cre) | 5 | 154 | 129 ± 14 | — |
| Runx1F/rd—Tg(Mx1-Cre) | 6 | 154 | 185§ ± 42 | 1.52∥/1.43¶ |
| Runx1F/F recipients* | 2 | 98† | 84 ± 21 | — |
| Runx1F/F—Tg(Mx1-Cre) recipients* | 4 | 98† | 128 ± 10 | 1.53 |
Genotype . | No. mice . | Days after pIpC . | Spleen weight, mg, mean ± SD . | Fold increase . |
|---|---|---|---|---|
| Runx1F/F | 7 | 60-273 | 153 ± 48 | — |
| Runx1F/F—Tg(Mx1-Cre) | 9 | 91-273 | 318‡ ± 195 | 2.08 |
| Runx1F/+ | 4 | 154 | 122 ± 26 | — |
| Runx1F/rd and Runx1F/+—Tg(Mx1-Cre) | 5 | 154 | 129 ± 14 | — |
| Runx1F/rd—Tg(Mx1-Cre) | 6 | 154 | 185§ ± 42 | 1.52∥/1.43¶ |
| Runx1F/F recipients* | 2 | 98† | 84 ± 21 | — |
| Runx1F/F—Tg(Mx1-Cre) recipients* | 4 | 98† | 128 ± 10 | 1.53 |
Mice that underwent transplantation with Runx1F/F or Runx1F/FTg(Mx1-Cre) marrow in the absence of competitor marrow.
Days after transplantation.
Comparison with Runx1F/F (P < .01; Mann-Whitney U test).
Comparison with Runx1F/+ (P = .033). Comparison with Runx1F/rd and Runx1F/+—Tg(Mx1-Cre) (P = .068; Mann-Whitney U test).
Comparison with Runx1F/+.
Comparison with Runx1F/rd and Runx1F/+—Tg(Mx1-Cre).