Patient characteristics
. | LTNPs, no treatment required . | First-line patients, given highly active antiretroviral therapy . | Salvage therapy patients, given HAART following at least 4 previous courses . |
|---|---|---|---|
| CD4 count, median cells/mm3 (interquartile range) | 701 (447-793) | 194 (94-261) | 78 (48-107) |
| HIV viral load, median copies/mL (interquartile range) | 640 (< 50-1826) | 1487 (84-44 910) | 103 090 (53 246-361 326) |
. | LTNPs, no treatment required . | First-line patients, given highly active antiretroviral therapy . | Salvage therapy patients, given HAART following at least 4 previous courses . |
|---|---|---|---|
| CD4 count, median cells/mm3 (interquartile range) | 701 (447-793) | 194 (94-261) | 78 (48-107) |
| HIV viral load, median copies/mL (interquartile range) | 640 (< 50-1826) | 1487 (84-44 910) | 103 090 (53 246-361 326) |
CD4 counts were measured by staining whole blood with murine anti-human monoclonal antibodies to CD4 (TetraOne; Beckman Coulter, High Wycombe, United Kingdom) with analysis on an Epics XL-MCL (Beckman Coulter) flow cytometer. Viral loads in patient plasma was measured using the Quantiplex HIV RNA 3.0 (Chiron bDNA) assay with a lower limit of detection of 50 HIV-1 copies/mL (Chiron Diagnostics, Halstead, United Kingdom).