Genes down-regulated in clo mutant embryos
GenBank ID . | Microarray ratio . | RT-PCR ratio . | Gene . | Chromosome . | Genomic region . |
|---|---|---|---|---|---|
| BI704361 | 0 | 0.02 ± 0.01 | Zinc finger CW-type coiled-coil domain protein 3 (Zcw3)* | 20 | 14567660-14568523 |
| BI980779 | 0 | 0.24 ± 0.04 | Unknown | 14 | 11255408-11256040 |
| AW115759 | 0.04 | 0.01 | Novel, C1qR-like (crl), distantly similar to the complement C1q receptor precursor† | 17 | 6659458-6661171 |
| AF045432 | 0.04 | ND | T-cell acute lymphocytic leukemia 1 (tal1;scl)‡ | ND | ND |
| AI626636 | 0.07 | 0.04 ± 0.01 | Similar to adrenomedullin receptor (admr)† | 23 | 39810187-39812236 |
| U18311 | 0.08 | 0.01 ± 0.00 | GATA-binding protein 1 (gata1)‡ | ND | ND |
| AI793509 | 0.09 | ND | Novel ETS domain-containing protein (ETS1-related protein, etsrp)† | 16 | 33961499-33966546 |
| AF157109 | 0.09 | 0.23 | Draculin (drl)‡ | ND | ND |
| AI384298 | 0.13 | 0.17 ± 0.09 | Similar to scavenger receptor class F, member 1 (scarf1)*† | ND | ND |
| AI965222 | 0.16 | 0.04 ± 0.01 | Cadherin 5 (cdh5)† | 14 | 49119878-49123369 |
| AI105766 | 0.16 | 0.35 ± 0.07 | Similar to aquaporin 8† | 12 | 15316616-15376296 |
| AF191560 | 0.17 | 0.13 ± 0.02 | LIM domain only 2 (Imo2)‡ | ND | ND |
| AI353708 | 0.20 | ND | Unknown | ND | ND |
| AI959504 | 0.20 | 0.28 ± 0.01 | Similar to EGF, latrophilin and 7-TM domain protein 1 (etl1) | 11 | 6244483-6269257 |
| AJ011790 | 0.32 | 0.33 ± 0.08 | Claudin g | 24 | 13093172-13091270 |
| AW077654 | 0.32 | 0.01 | Spi1 (pu.1)‡ | ND | ND |
| BI896312 | 0.38 | 0.68 ± 0.03 | Friend leukemia integration 1 (fli1)‡ | ND | ND |
| AI353083 | 0.40 | ND | Hemoglobin alpha embryonic-3 (hbae3)‡ | ND | ND |
| BI842407 | 0.44 | 0.39 ± 0.02 | Unknown | 13 | 15277643-15277861 |
| AI601685 | 0.45 | 0.53 ± 0.03 | Similar to dual specificity phosphatase 5 (dusp5)† | 22 | 30622712-30633737 |
| BE693186 | 0.45 | ND | Hemoglobin alpha embryonic-1 (hbae1)‡ | ND | ND |
| AJ249590 | 0.48 | ND | Friend leukemia integration 1 (fli1)‡ | ND | ND |
| AF262978 | 0.49 | ND | Kruppel-like factor 4 (klf4; biklf)‡ | ND | ND |
| AF082662 | 0.49 | ND | Hemoglobin beta embryonic-1 (hbbe1)‡ | ND | ND |
| AJ236884 | 0.56 | 0.56 ± 0.09 | Retinol binding protein 4 (rbp4)† | ND | ND |
GenBank ID . | Microarray ratio . | RT-PCR ratio . | Gene . | Chromosome . | Genomic region . |
|---|---|---|---|---|---|
| BI704361 | 0 | 0.02 ± 0.01 | Zinc finger CW-type coiled-coil domain protein 3 (Zcw3)* | 20 | 14567660-14568523 |
| BI980779 | 0 | 0.24 ± 0.04 | Unknown | 14 | 11255408-11256040 |
| AW115759 | 0.04 | 0.01 | Novel, C1qR-like (crl), distantly similar to the complement C1q receptor precursor† | 17 | 6659458-6661171 |
| AF045432 | 0.04 | ND | T-cell acute lymphocytic leukemia 1 (tal1;scl)‡ | ND | ND |
| AI626636 | 0.07 | 0.04 ± 0.01 | Similar to adrenomedullin receptor (admr)† | 23 | 39810187-39812236 |
| U18311 | 0.08 | 0.01 ± 0.00 | GATA-binding protein 1 (gata1)‡ | ND | ND |
| AI793509 | 0.09 | ND | Novel ETS domain-containing protein (ETS1-related protein, etsrp)† | 16 | 33961499-33966546 |
| AF157109 | 0.09 | 0.23 | Draculin (drl)‡ | ND | ND |
| AI384298 | 0.13 | 0.17 ± 0.09 | Similar to scavenger receptor class F, member 1 (scarf1)*† | ND | ND |
| AI965222 | 0.16 | 0.04 ± 0.01 | Cadherin 5 (cdh5)† | 14 | 49119878-49123369 |
| AI105766 | 0.16 | 0.35 ± 0.07 | Similar to aquaporin 8† | 12 | 15316616-15376296 |
| AF191560 | 0.17 | 0.13 ± 0.02 | LIM domain only 2 (Imo2)‡ | ND | ND |
| AI353708 | 0.20 | ND | Unknown | ND | ND |
| AI959504 | 0.20 | 0.28 ± 0.01 | Similar to EGF, latrophilin and 7-TM domain protein 1 (etl1) | 11 | 6244483-6269257 |
| AJ011790 | 0.32 | 0.33 ± 0.08 | Claudin g | 24 | 13093172-13091270 |
| AW077654 | 0.32 | 0.01 | Spi1 (pu.1)‡ | ND | ND |
| BI896312 | 0.38 | 0.68 ± 0.03 | Friend leukemia integration 1 (fli1)‡ | ND | ND |
| AI353083 | 0.40 | ND | Hemoglobin alpha embryonic-3 (hbae3)‡ | ND | ND |
| BI842407 | 0.44 | 0.39 ± 0.02 | Unknown | 13 | 15277643-15277861 |
| AI601685 | 0.45 | 0.53 ± 0.03 | Similar to dual specificity phosphatase 5 (dusp5)† | 22 | 30622712-30633737 |
| BE693186 | 0.45 | ND | Hemoglobin alpha embryonic-1 (hbae1)‡ | ND | ND |
| AJ249590 | 0.48 | ND | Friend leukemia integration 1 (fli1)‡ | ND | ND |
| AF262978 | 0.49 | ND | Kruppel-like factor 4 (klf4; biklf)‡ | ND | ND |
| AF082662 | 0.49 | ND | Hemoglobin beta embryonic-1 (hbbe1)‡ | ND | ND |
| AJ236884 | 0.56 | 0.56 ± 0.09 | Retinol binding protein 4 (rbp4)† | ND | ND |
Ratios of gene expression in clo mutant embryos versus their siblings were calculated. Chromosomal location was determined using the zebrafish genome sequencing assembly Zv4 release.
ND indicates not determined.
Annotation of these noncoding 3′ UTR sequences is based on their genomic location in the immediate vicinity of the corresponding gene.
Genes selected for further characterization.
Zebrafish genes previously known to be expressed in hematopoietic or vascular endothelial cells.