Weights and relative fractions of 59Fe in the organs and peripheral blood of rats at 6 hours after oral administration of 59Fe by gavage
. | Vehicle . | E2 1 mg/kg . |
|---|---|---|
| Weight, g | ||
| Duodenum | ||
| Basal Diet | 0.51 ± 0.05 | 0.56 ± 0.07 |
| Low-Iron Diet | 0.48 ± 0.04 | 0.56 ± 0.05* |
| Jejunum | ||
| Basal Diet | 1.38 ± 0.08 | 1.38 ± 0.15 |
| Low-Iron Diet | 1.24 ± 0.06† | 1.39 ± 0.14* |
| Ileum | ||
| Basal Diet | 1.33 ± 0.18 | 1.33 ± 0.17 |
| Low-Iron Diet | 1.26 ± 0.13 | 1.36 ± 0.13 |
| Liver | ||
| Basal Diet | 4.3 ± 0.4 | 5.5 ± 0.4* |
| Low-Iron Diet | 3.8 ± 0.4 | 5.1 ± 0.3* |
| 59Fe fraction, % | ||
| Duodenum | ||
| Basal Diet | 6.8 ± 1.5 | 10.9 ± 3.4* |
| Low-Iron Diet | 2.3 ± 0.9† | 3.9 ± 0.7*† |
| Jejunum | ||
| Basal Diet | 6.2 ± 1.1 | 10.8 ± 2.1* |
| Low-Iron Diet | 5.2 ± 2.0 | 6.7 ± 2.3† |
| Ileum | ||
| Basal Diet | 0.9 ± 0.2 | 1.8 ± 0.6* |
| Low-Iron Diet | 1.6 ± 0.3† | 2.3 ± 0.6* |
| Blood, 1 mL | ||
| Basal Diet | 0.3 ± 0.2 | 0.3 ± 0.1 |
| Low-Iron Diet | 0.8 ± 0.2† | 1.4 ± 0.3*† |
| Liver | ||
| Basal Diet | 5.4 ± 1.5 | 7.3 ± 4.5 |
| Low-Iron Diet | 8.5 ± 1.4 | 29.6 ± 13.6*† |
. | Vehicle . | E2 1 mg/kg . |
|---|---|---|
| Weight, g | ||
| Duodenum | ||
| Basal Diet | 0.51 ± 0.05 | 0.56 ± 0.07 |
| Low-Iron Diet | 0.48 ± 0.04 | 0.56 ± 0.05* |
| Jejunum | ||
| Basal Diet | 1.38 ± 0.08 | 1.38 ± 0.15 |
| Low-Iron Diet | 1.24 ± 0.06† | 1.39 ± 0.14* |
| Ileum | ||
| Basal Diet | 1.33 ± 0.18 | 1.33 ± 0.17 |
| Low-Iron Diet | 1.26 ± 0.13 | 1.36 ± 0.13 |
| Liver | ||
| Basal Diet | 4.3 ± 0.4 | 5.5 ± 0.4* |
| Low-Iron Diet | 3.8 ± 0.4 | 5.1 ± 0.3* |
| 59Fe fraction, % | ||
| Duodenum | ||
| Basal Diet | 6.8 ± 1.5 | 10.9 ± 3.4* |
| Low-Iron Diet | 2.3 ± 0.9† | 3.9 ± 0.7*† |
| Jejunum | ||
| Basal Diet | 6.2 ± 1.1 | 10.8 ± 2.1* |
| Low-Iron Diet | 5.2 ± 2.0 | 6.7 ± 2.3† |
| Ileum | ||
| Basal Diet | 0.9 ± 0.2 | 1.8 ± 0.6* |
| Low-Iron Diet | 1.6 ± 0.3† | 2.3 ± 0.6* |
| Blood, 1 mL | ||
| Basal Diet | 0.3 ± 0.2 | 0.3 ± 0.1 |
| Low-Iron Diet | 0.8 ± 0.2† | 1.4 ± 0.3*† |
| Liver | ||
| Basal Diet | 5.4 ± 1.5 | 7.3 ± 4.5 |
| Low-Iron Diet | 8.5 ± 1.4 | 29.6 ± 13.6*† |
The rats were administered E2 at 1 mg/kg 3 times a week for 2 months and fed the Basal Diet 5755 (vehicle group, n = 6; E2 group, n = 5) or the Low-Iron Purified Diet (vehicle group, n = 6; E2 group, n = 6) from TestDiet. Data are presented as mean ± SD.
P < .05 (compared with vehicle group).
P < .05 (compared with Basal Diet group).