Table 1.

IgG by time after first challenge


Mouse genotype

IgG by time after first challenge, μg/mL, mean ± SEM
-10 d
4 d
11 d
18 d
WT   102.6 ± 3.4   650.0 ± 87.8*  832.1 ± 97.0*  860.8 ± 211.4* 
KO
 
99.1 ± 3.7
 
694.0 ± 80.2*
 
717.7 ± 165.9*
 
853.6 ± 231.3*
 

Mouse genotype

IgG by time after first challenge, μg/mL, mean ± SEM
-10 d
4 d
11 d
18 d
WT   102.6 ± 3.4   650.0 ± 87.8*  832.1 ± 97.0*  860.8 ± 211.4* 
KO
 
99.1 ± 3.7
 
694.0 ± 80.2*
 
717.7 ± 165.9*
 
853.6 ± 231.3*
 

Total IgG concentration in the serum from individual mice (n = 3) was measured by an ELISA.

*

Difference is statistically significant (P < .001) compared with the value on day -10. Antigen-specific immune responses between MGL1-deficient mice and wild-type mice were almost identical.

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