scTCR-expressing cells in reconstituted C57BL/6 and MUC1 Tg mice
. | TCR reconstituted, mean % ± SD . | . | . | ||
|---|---|---|---|---|---|
| Cell type/surface marker . | Control* . | C57BL/6 . | MUC1 Tg . | ||
| T cells/CD3+ | 0.2 ± 0 | 6.4 ± 1.3 | 9.0 ± 5.7 | ||
| B cells/B220+ | 0.2 ± 0 | 9.7 ± 0.3 | 9.5 ± 1.6 | ||
| Granulocytes/GR-1+ | 0.2 ± 0.7 | 30.8 ± 21.5 | 27.4 ± 9.2 | ||
| NK cells/DX5+ | 0.1 ± 0 | 28.5 ± 4.3 | 18.5 ± 3.7 | ||
| Monocytes/F4/80+ | 0.1 ± 0.2 | 20.4 ± 5.0 | 14.6 ± 2.7 | ||
. | TCR reconstituted, mean % ± SD . | . | . | ||
|---|---|---|---|---|---|
| Cell type/surface marker . | Control* . | C57BL/6 . | MUC1 Tg . | ||
| T cells/CD3+ | 0.2 ± 0 | 6.4 ± 1.3 | 9.0 ± 5.7 | ||
| B cells/B220+ | 0.2 ± 0 | 9.7 ± 0.3 | 9.5 ± 1.6 | ||
| Granulocytes/GR-1+ | 0.2 ± 0.7 | 30.8 ± 21.5 | 27.4 ± 9.2 | ||
| NK cells/DX5+ | 0.1 ± 0 | 28.5 ± 4.3 | 18.5 ± 3.7 | ||
| Monocytes/F4/80+ | 0.1 ± 0.2 | 20.4 ± 5.0 | 14.6 ± 2.7 | ||
Analysis was performed 6 weeks after reconstitution with scTCR-transduced BM using EGFP as a marker of scTCR expression.
C57BL/6 untreated mice.