Table 4. Correlation between COX-2... | American Society of Hematology

Table 4.

Correlation between COX-2 expression and clinical parameters

	COX-2 positive	COX-2 negative
Mean age, y, ± SD	56.5 ± 10.5	55.4 ± 9.2
Female, %	51.7	35.3
Salmon and Durie stage, %
Stage I	3.4	4.6
Stage II	20.7	32.5
Stage III	75.8	63.0
Mean β2-microglobulin, μg/L, ± SD^*	5.7 ± 9.2	6.0 ± 5.9
Mean creatinine, mg/dL, ± SD	1.54 ± 1.5	1.53 ± 1.4
Mean Hb level, g/dL, ± SD	10.4 ± 2.2	11.0 ± 2.2
Bone lesions at least 1, %	72.4	72.3
Mean BM PCs, %, ± SD	46.6 ± 24.3	47.7 ± 20.8
Del13q, %†	55.5	44.4

	COX-2 positive	COX-2 negative
Mean age, y, ± SD	56.5 ± 10.5	55.4 ± 9.2
Female, %	51.7	35.3
Salmon and Durie stage, %
Stage I	3.4	4.6
Stage II	20.7	32.5
Stage III	75.8	63.0
Mean β2-microglobulin, μg/L, ± SD^*	5.7 ± 9.2	6.0 ± 5.9
Mean creatinine, mg/dL, ± SD	1.54 ± 1.5	1.53 ± 1.4
Mean Hb level, g/dL, ± SD	10.4 ± 2.2	11.0 ± 2.2
Bone lesions at least 1, %	72.4	72.3
Mean BM PCs, %, ± SD	46.6 ± 24.3	47.7 ± 20.8
Del13q, %†	55.5	44.4

P values were not significant for any variable.

SD indicates standard deviation; Hb, hemoglobin; BM, bone marrow; PCs, plasma cells.

β2-microglobulin was available in 77 patients.

Assessed by fluorescence in situ hybridization on 36 patients.