Clinical features of patients at diagnosis, as assessed by WB
. | No. . | % . |
|---|---|---|
| Total | 94 | 100 |
| Mean age, y (range) | 56 (34-77) | NA |
| Female | 38 | 40.4 |
| Mean BM PCs, % (range) | 47 (5-99) | NA |
| M component | ||
| IgG | 53 | 56.4 |
| IgA | 22 | 23.4 |
| Light chain | 17 | 18.1 |
| Nonsecretory | 2 | 2.1 |
| K | 60 | 65.2 |
| Mean Hb level, g/dL (range) | 11 (5.6-16) | NA |
| Bone lytic lesions | ||
| 0 | 26 | 27.6 |
| 1 or more | 68 | 72.3 |
| Salmon and Durie stage | ||
| I | 4 | 4.2 |
| II | 27 | 28.7 |
| III | 63 | 67.0 |
| Mean creatinine level, mg/dL (range) | 2 (0.4-8.4) | NA |
| Del13q* | 18 | 50.0 |
| Mean 2-microglobulin level, g/L (range)† | 5 (1.1-22.8) | NA |
| First-line treatment | ||
| Conventional | 28 | 29.8 |
| Thalidomide plus conventional | 4 | 4.2 |
| Autologous or allogeneic SCT | 62 | 66.0 |
. | No. . | % . |
|---|---|---|
| Total | 94 | 100 |
| Mean age, y (range) | 56 (34-77) | NA |
| Female | 38 | 40.4 |
| Mean BM PCs, % (range) | 47 (5-99) | NA |
| M component | ||
| IgG | 53 | 56.4 |
| IgA | 22 | 23.4 |
| Light chain | 17 | 18.1 |
| Nonsecretory | 2 | 2.1 |
| K | 60 | 65.2 |
| Mean Hb level, g/dL (range) | 11 (5.6-16) | NA |
| Bone lytic lesions | ||
| 0 | 26 | 27.6 |
| 1 or more | 68 | 72.3 |
| Salmon and Durie stage | ||
| I | 4 | 4.2 |
| II | 27 | 28.7 |
| III | 63 | 67.0 |
| Mean creatinine level, mg/dL (range) | 2 (0.4-8.4) | NA |
| Del13q* | 18 | 50.0 |
| Mean 2-microglobulin level, g/L (range)† | 5 (1.1-22.8) | NA |
| First-line treatment | ||
| Conventional | 28 | 29.8 |
| Thalidomide plus conventional | 4 | 4.2 |
| Autologous or allogeneic SCT | 62 | 66.0 |