Expression of selected genes involved in DNA repair and cell-cycle control in hTERT-transduced T cells
Accession no. . | Gene description . | Symbol . | Affymetrix ID . | GFP PD32 . | GFP PD47 . | hTERT PD44 . | hTERT PD80 . |
|---|---|---|---|---|---|---|---|
| NM_000546 | Tumor protein p53 (Li-Fraumeni syndrome) | TP53 | 201746_at | 1784 | 1501 | 1752 | 1709 |
| U38945 | Cyclin-dependent kinase inhibitor 2A | CDKN2A | 209644_x_at | 630 | 913 | 1135 | 1239 |
| NM_007295 | Breast cancer 1, early onset | BRCA1 | 204531_s_at | 503 | 415 | 452 | 445 |
| U49844 | Ataxia telangiectasia and Rad3 related | ATR | 209902_at | 421 | 248 | 437 | 373 |
| NM_004629 | Fanconi anemia, complementation group G | FANCG | 203564_at | 1411 | 1223 | 817 | 901 |
| AI796269 | Nijmegen breakage syndrome 1 (nibrin) | NBS1 | 202905_x_at | 1202 | 1185 | 1427 | 1251 |
| NM_002853 | RAD1 homolog (Schizosaccharomyces pombe) | RAD1 | 204461_x_at | 803 | 731 | 776 | 915 |
| NM_002894 | Retinoblastoma-binding protein 8 | RBBP8 | 203344_s_at | 2275 | 2428 | 1971 | 3392 |
| D80000 | SMC1 structural maintenance of chromosomes 1-like 1 (yeast) | SMC1L1 | 201589_at | 5093 | 4578 | 4021 | 5308 |
| NM_001274 | CHK1 checkpoint homolog (S pombe) | CHEK1 | 205394_at | 1202 | 1087 | 810 | 1231 |
| NM_001924 | Growth arrest and DNA damage-inducible, α | GADD45A | 203725_at | 5790 | 4147 | 6245 | 3140 |
| BC006325 | G2 and S-phase expressed 1/G2 and S-phase expressed 1 | GTSE1 | 211040_x_at | 1989 | 1788 | 2203 | 2035 |
| AI968626 | HUS1 checkpoint homolog (S pombe) | HUS1 | 204883_s_at | 851 | 495 | 488 | 613* |
| BC004153 | Poly(rC)-binding protein 4 | PCBP4 | 209361_s_at | 283 | 356* | 645 | 607* |
| U83981 | Protein phosphatase 1, regulatory (inhibitor) subunit 15A | PPP1R15A | 37028_at | 600 | 790 | 1183 | 1285 |
| AF085736 | RAD17 homolog (S pombe) | RAD17 | 211228_s_at | 1613 | 1024 | 1333 | 1196 |
| NM_004584 | RAD9 homolog A (S pombe) | RAD9A | 204828_at | 819 | 777 | 842 | 842 |
| NM_014454 | Sestrin 1 | SESN1 | 218346_s_at | 1047 | 1239 | 1055 | 742 |
| U82828 | Ataxia telangiectasia mutated | ATM | 212672_at | 872 | 938 | 1017 | 1019 |
| NM_002592 | Proliferating cell nuclear antigen | PCNA | 201202_at | 12590 | 13100 | 10539 | 11530 |
| M19701 | Retinoblastoma 1 (including osteosarcoma) | RB1 | 211540_s_at | 770 | 625 | 651* | 756 |
| U19599 | BCL2-associated X protein | BAX | 211833_s_at | 2118 | 2326 | 2332 | 1852 |
| NM_013229 | Apoptotic protease-activating factor | APAF1 | 204859_s_at | 783 | 674 | 563 | 743 |
| NM_000389 | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | CDKN1A | 202284_s_at | 3126 | 4148 | 4935 | 3732 |
| NM_002467 | v-myc myelocytomatosis viral oncogene homolog (avian) | MYC | 202431_s_at | 1153 | 959 | 1265 | 682 |
| NM_000633 | B-cell CLL/lymphoma 2 | BCL2 | 203685_at | 4220 | 4929 | 4231 | 3746 |
| AL117381 | BCL2-like 1 | BCL2L1 | 212312_at | 1015 | 1507 | 1498 | 1067 |
| NM_005157 | v-abl Abelson murine leukemia viral oncogene homolog 1 | ABL1 | 202123_s_at | 828 | 612 | 786 | 565 |
| NM_006265 | RAD21 homolog (S pombe) | RAD21 | 200608_s_at | 8995 | 9550 | 7463 | 9790 |
| NM_000249 | mutL homolog 1, colon cancer, nonpolyposis type 2 (Escherichia coli) | MLH1 | 202520_s_at | 3214 | 2736 | 2182 | 2810 |
| NM_014430 | Cell death-inducing DFFA-like effector b | CIDEB | 221188_s_at | 1087 | 858 | 1249 | 541* |
| NM_004208 | Programmed cell death 8 (apoptosis-inducing factor) | PDCD8 | 205512_s_at | 965 | 1003 | 1209 | 1007 |
| BF062629 | Ras-induced senescence 1 | RIS1 | 213338_at | 440 | 572 | 1267 | 508 |
Accession no. . | Gene description . | Symbol . | Affymetrix ID . | GFP PD32 . | GFP PD47 . | hTERT PD44 . | hTERT PD80 . |
|---|---|---|---|---|---|---|---|
| NM_000546 | Tumor protein p53 (Li-Fraumeni syndrome) | TP53 | 201746_at | 1784 | 1501 | 1752 | 1709 |
| U38945 | Cyclin-dependent kinase inhibitor 2A | CDKN2A | 209644_x_at | 630 | 913 | 1135 | 1239 |
| NM_007295 | Breast cancer 1, early onset | BRCA1 | 204531_s_at | 503 | 415 | 452 | 445 |
| U49844 | Ataxia telangiectasia and Rad3 related | ATR | 209902_at | 421 | 248 | 437 | 373 |
| NM_004629 | Fanconi anemia, complementation group G | FANCG | 203564_at | 1411 | 1223 | 817 | 901 |
| AI796269 | Nijmegen breakage syndrome 1 (nibrin) | NBS1 | 202905_x_at | 1202 | 1185 | 1427 | 1251 |
| NM_002853 | RAD1 homolog (Schizosaccharomyces pombe) | RAD1 | 204461_x_at | 803 | 731 | 776 | 915 |
| NM_002894 | Retinoblastoma-binding protein 8 | RBBP8 | 203344_s_at | 2275 | 2428 | 1971 | 3392 |
| D80000 | SMC1 structural maintenance of chromosomes 1-like 1 (yeast) | SMC1L1 | 201589_at | 5093 | 4578 | 4021 | 5308 |
| NM_001274 | CHK1 checkpoint homolog (S pombe) | CHEK1 | 205394_at | 1202 | 1087 | 810 | 1231 |
| NM_001924 | Growth arrest and DNA damage-inducible, α | GADD45A | 203725_at | 5790 | 4147 | 6245 | 3140 |
| BC006325 | G2 and S-phase expressed 1/G2 and S-phase expressed 1 | GTSE1 | 211040_x_at | 1989 | 1788 | 2203 | 2035 |
| AI968626 | HUS1 checkpoint homolog (S pombe) | HUS1 | 204883_s_at | 851 | 495 | 488 | 613* |
| BC004153 | Poly(rC)-binding protein 4 | PCBP4 | 209361_s_at | 283 | 356* | 645 | 607* |
| U83981 | Protein phosphatase 1, regulatory (inhibitor) subunit 15A | PPP1R15A | 37028_at | 600 | 790 | 1183 | 1285 |
| AF085736 | RAD17 homolog (S pombe) | RAD17 | 211228_s_at | 1613 | 1024 | 1333 | 1196 |
| NM_004584 | RAD9 homolog A (S pombe) | RAD9A | 204828_at | 819 | 777 | 842 | 842 |
| NM_014454 | Sestrin 1 | SESN1 | 218346_s_at | 1047 | 1239 | 1055 | 742 |
| U82828 | Ataxia telangiectasia mutated | ATM | 212672_at | 872 | 938 | 1017 | 1019 |
| NM_002592 | Proliferating cell nuclear antigen | PCNA | 201202_at | 12590 | 13100 | 10539 | 11530 |
| M19701 | Retinoblastoma 1 (including osteosarcoma) | RB1 | 211540_s_at | 770 | 625 | 651* | 756 |
| U19599 | BCL2-associated X protein | BAX | 211833_s_at | 2118 | 2326 | 2332 | 1852 |
| NM_013229 | Apoptotic protease-activating factor | APAF1 | 204859_s_at | 783 | 674 | 563 | 743 |
| NM_000389 | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | CDKN1A | 202284_s_at | 3126 | 4148 | 4935 | 3732 |
| NM_002467 | v-myc myelocytomatosis viral oncogene homolog (avian) | MYC | 202431_s_at | 1153 | 959 | 1265 | 682 |
| NM_000633 | B-cell CLL/lymphoma 2 | BCL2 | 203685_at | 4220 | 4929 | 4231 | 3746 |
| AL117381 | BCL2-like 1 | BCL2L1 | 212312_at | 1015 | 1507 | 1498 | 1067 |
| NM_005157 | v-abl Abelson murine leukemia viral oncogene homolog 1 | ABL1 | 202123_s_at | 828 | 612 | 786 | 565 |
| NM_006265 | RAD21 homolog (S pombe) | RAD21 | 200608_s_at | 8995 | 9550 | 7463 | 9790 |
| NM_000249 | mutL homolog 1, colon cancer, nonpolyposis type 2 (Escherichia coli) | MLH1 | 202520_s_at | 3214 | 2736 | 2182 | 2810 |
| NM_014430 | Cell death-inducing DFFA-like effector b | CIDEB | 221188_s_at | 1087 | 858 | 1249 | 541* |
| NM_004208 | Programmed cell death 8 (apoptosis-inducing factor) | PDCD8 | 205512_s_at | 965 | 1003 | 1209 | 1007 |
| BF062629 | Ras-induced senescence 1 | RIS1 | 213338_at | 440 | 572 | 1267 | 508 |
Call: absent.