Table 1. IC 50 values of different drugs... | American Society of Hematology

Table 1.

IC₅₀ values of different drugs in the presence of R115777 in RPMI8226/S cells

R115777, nM	Paclitaxel, nM	Docetaxel, nM	Gemcitibine, nM	Doxorubicin, nM	5-FU, μM	Cis-platinum, μM
0	2.5	0.60	10	100	5.0	8.0
10	1.2	0.35	9.0	100	5.0	7.8
30	1.0	0.25	8.0	100	5.0	7.5
100	0.8	0.20	7.0	70	5.0	7.0

R115777, nM	Paclitaxel, nM	Docetaxel, nM	Gemcitibine, nM	Doxorubicin, nM	5-FU, μM	Cis-platinum, μM
0	2.5	0.60	10	100	5.0	8.0
10	1.2	0.35	9.0	100	5.0	7.8
30	1.0	0.25	8.0	100	5.0	7.5
100	0.8	0.20	7.0	70	5.0	7.0

Data obtained with MTT assays with 72-hour incubation of drugs.