Table 2.

Characteristics of MDS patients with the G-CSF-R 785Glu/Lys genotype


Patient no.

Age, y/sex

FAB classification

Cytogenetics

No. cytopenias

Percentage of BM blasts

IPSS score
1   60/M   RAEB   46,XY,inv(3)(q21q26),del(5)(q15q33),del(17)(p13)   3   6   2  
2   62/M   RAEB   49,XY,del(1)(p34),+del(1)(p34),+8,+14   1   20   2.5  
3   64/M   RAEB   46,XY   1   14   1.5  
4   66/M   RAEB   45,XY,del(5)(q13q33),der(12)t(12;?)(p13?,?),-18,-20,+mar   2   10   2  
5   71/F   RAEB   47,XX,+13   2   20   2.5  
6   73/F   RAEB   46,XX   1   20   1.5  
7   73/F   RARS   46,XX   0   < 5   0  
8
 
84/F
 
AML following MDS
 
47,XX,+8
 
2
 
> 30
 
NA
 

Patient no.

Age, y/sex

FAB classification

Cytogenetics

No. cytopenias

Percentage of BM blasts

IPSS score
1   60/M   RAEB   46,XY,inv(3)(q21q26),del(5)(q15q33),del(17)(p13)   3   6   2  
2   62/M   RAEB   49,XY,del(1)(p34),+del(1)(p34),+8,+14   1   20   2.5  
3   64/M   RAEB   46,XY   1   14   1.5  
4   66/M   RAEB   45,XY,del(5)(q13q33),der(12)t(12;?)(p13?,?),-18,-20,+mar   2   10   2  
5   71/F   RAEB   47,XX,+13   2   20   2.5  
6   73/F   RAEB   46,XX   1   20   1.5  
7   73/F   RARS   46,XX   0   < 5   0  
8
 
84/F
 
AML following MDS
 
47,XX,+8
 
2
 
> 30
 
NA
 

IPSS indicates International Prognostic Scoring System for MDS; NA, not applicable.

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