Table 3.

Anti-B-CLL reactivity of autologous anti-third-party CTLs



B-CLL

B-CLL + autologous CTL
Patient no.
Mice per group, n
% CD 19/20+CD5+
Mice per group, n
% CD 19/20+CD5+
% B-CLL eradication*
1   3   3.6   3   0.9   75 
2   4   5.7   1   3.35   42 (NS)  
3   5   66.3   5   0.9   98.6 
4   1   40.15   1   0.85   97.8 (NS)  
5   7   14.4   6   6.1   57.6 
6
 
3
 
28.1
 
3
 
13.5
 
51.9
 


B-CLL

B-CLL + autologous CTL
Patient no.
Mice per group, n
% CD 19/20+CD5+
Mice per group, n
% CD 19/20+CD5+
% B-CLL eradication*
1   3   3.6   3   0.9   75 
2   4   5.7   1   3.35   42 (NS)  
3   5   66.3   5   0.9   98.6 
4   1   40.15   1   0.85   97.8 (NS)  
5   7   14.4   6   6.1   57.6 
6
 
3
 
28.1
 
3
 
13.5
 
51.9
 

NS indicates not significant.

*

This value was calculated as follows: (% untreated - % treated/untreated) × 100.

Pf < .05.

Pf < 5 × 10−5.

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