Table 1.

Anti-B-CLL reactivity of allogeneic anti—third-party CTLs



B-CLL

B-CLL + anti—third-party CTL
Patient no.
Mice per group, n
% CD19/20+CD5+
Mice per group, n
% CD19/20+CD5+
% B-CLL eradication*
1   3   3.6   3   0.2   94.4 
2   4   5.7   5   2.9   49.1 
3   2   0.22   2   0.045   79.5 (NS)  
4   2   54.9   2   0.7   98.7 (NS)  
5   5   18.6   5   3.1   83.3 
6
 
3
 
56.7
 
5
 
4.1
 
92.7§
 


B-CLL

B-CLL + anti—third-party CTL
Patient no.
Mice per group, n
% CD19/20+CD5+
Mice per group, n
% CD19/20+CD5+
% B-CLL eradication*
1   3   3.6   3   0.2   94.4 
2   4   5.7   5   2.9   49.1 
3   2   0.22   2   0.045   79.5 (NS)  
4   2   54.9   2   0.7   98.7 (NS)  
5   5   18.6   5   3.1   83.3 
6
 
3
 
56.7
 
5
 
4.1
 
92.7§
 

NS indicates not significant.

*

This value was calculated as follows: [% untreated − % treated/untreated] × 100.

Pf < .05.

Pf < .0005.

§

Pf < 5 × 10−5.

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