Combination index values for induction of apoptosis
Cell lines . | Drugs (μM) . | Cl . | Description . |
|---|---|---|---|
| 32D-p 185 | MPA (1) + imatinib (0.5) | 0.47 (± 0.13) | Synergism |
| MPA (1) + imatinib (1) | 0.28 (± 0.07) | Strong synergism | |
| MPA (2) + imatinib (0.5) | 0.34 (± 0.04) | Synergism | |
| MPA (2) + imatinib (1) | 0.21 (± 0.09) | Strong synergism | |
| K562 | MPA (1) + imatinib (0.25) | 0.04 (± 0.04) | Very strong synergism |
| MPA (2) + imatinib (0.5) | 0.04 (± 0.05) | Very strong synergism | |
| MPA (4) + imatinib (1) | 0.06 (± 0.08) | Very strong synergism |
Cell lines . | Drugs (μM) . | Cl . | Description . |
|---|---|---|---|
| 32D-p 185 | MPA (1) + imatinib (0.5) | 0.47 (± 0.13) | Synergism |
| MPA (1) + imatinib (1) | 0.28 (± 0.07) | Strong synergism | |
| MPA (2) + imatinib (0.5) | 0.34 (± 0.04) | Synergism | |
| MPA (2) + imatinib (1) | 0.21 (± 0.09) | Strong synergism | |
| K562 | MPA (1) + imatinib (0.25) | 0.04 (± 0.04) | Very strong synergism |
| MPA (2) + imatinib (0.5) | 0.04 (± 0.05) | Very strong synergism | |
| MPA (4) + imatinib (1) | 0.06 (± 0.08) | Very strong synergism |
Cl values were obtained by annexin V staining analyzed by flow cytometry. Data represent the mean ± SD of 3 independent experiments.