Summary of structure and expression analyses of the transgenes in transgenic mice
Construct/Line . | No. Repeats* . | No. Ends* . | No. copies . | γRNA/mu αRNA** . | γRNA/mu αRNA/copy** . | |
|---|---|---|---|---|---|---|
| HS-40/βpr/γ gene | ||||||
| A | 4 | 1 | 5 | 0.07 | 0.06 | |
| B | 22 | 4 | 26 | 0.13 | 0.02 | |
| C | 12 | 3 | 15 | 0.08 | 0.02 | |
| D | 2 | 1 | 3 | 0.05 | 0.06 | |
| HS-40(mut)/βpr/γ gene | ||||||
| E | 70 | 1 | 71 | 0.15 | 0.01 | |
| F | 29 | 2 | 31 | 0.86 | 0.11 | |
| μLCR/βpr/γ gene | ||||||
| G | — | — | 3 | 34.2 | 45.6 | |
| H | — | — | 12 | 30.5 | 10.2 | |
| I | — | — | 3 | 1.6 | 2.1 | |
| J | — | — | 2 | 7.6 | 15.3 | |
| HS-40/βpr/γ gene/hHS5 | ||||||
| K | 51 | 1 | 52 | 0.3 | 0.02 | |
| L | 2 | 1 | 3 | 2.7 | 3.6 | |
| M | 49 | 2 | 51 | 3.4 | 0.42 | |
| N | 8 | 1 | 9 | 0.6 | 0.27 | |
| O | 0 | 1 | 1 | 0.1 | 0.38 | |
| cHS4/HS-40/βpr/γ gene | ||||||
| P | 9 | 1 | 10 | 0.03 | 0.01 | |
| Q | 4 | 1 | 5 | 0.16 | 0.12 | |
| R | 23 | 3 | 26 | 0.46 | 0.07 | |
| S | 15 | 1 | 16 | 0.27 | 0.07 | |
Construct/Line . | No. Repeats* . | No. Ends* . | No. copies . | γRNA/mu αRNA** . | γRNA/mu αRNA/copy** . | |
|---|---|---|---|---|---|---|
| HS-40/βpr/γ gene | ||||||
| A | 4 | 1 | 5 | 0.07 | 0.06 | |
| B | 22 | 4 | 26 | 0.13 | 0.02 | |
| C | 12 | 3 | 15 | 0.08 | 0.02 | |
| D | 2 | 1 | 3 | 0.05 | 0.06 | |
| HS-40(mut)/βpr/γ gene | ||||||
| E | 70 | 1 | 71 | 0.15 | 0.01 | |
| F | 29 | 2 | 31 | 0.86 | 0.11 | |
| μLCR/βpr/γ gene | ||||||
| G | — | — | 3 | 34.2 | 45.6 | |
| H | — | — | 12 | 30.5 | 10.2 | |
| I | — | — | 3 | 1.6 | 2.1 | |
| J | — | — | 2 | 7.6 | 15.3 | |
| HS-40/βpr/γ gene/hHS5 | ||||||
| K | 51 | 1 | 52 | 0.3 | 0.02 | |
| L | 2 | 1 | 3 | 2.7 | 3.6 | |
| M | 49 | 2 | 51 | 3.4 | 0.42 | |
| N | 8 | 1 | 9 | 0.6 | 0.27 | |
| O | 0 | 1 | 1 | 0.1 | 0.38 | |
| cHS4/HS-40/βpr/γ gene | ||||||
| P | 9 | 1 | 10 | 0.03 | 0.01 | |
| Q | 4 | 1 | 5 | 0.16 | 0.12 | |
| R | 23 | 3 | 26 | 0.46 | 0.07 | |
| S | 15 | 1 | 16 | 0.27 | 0.07 | |
*—, not detected; **mu, murine.