Table 3.

Disease status until the time of allogeneic stem cell transplantation




Imatinib group (n = 29)

Historical group (n = 33)

P
After induction therapy    
   CR1 (%)   23 (79.3)   27 (81.8)   .803  
   Refractory (%)   6 (20.7)   6 (18.2)   
After consolidation therapy    
   Sustained CR1 (%)   22/23 (95.7)   16/27 (59.3)   .003  
   Relapse (%)   1/23 (4.3)   11/27 (40.7)   
After salvage therapy    
   CR1 (%)   3/6 (50.0)   1/6 (16.7)   .545  
   Refractory (%)   3/6 (50.0)   5/6 (83.3)   
Pretransplantation disease status    
   CR1 (%)*  25 (86.2)  17 (51.5)   .004  
   CR2 (%)   0   9 (27.3)   
   Refractory (%)
 
4 (13.8)
 
7 (21.2)
 

 



Imatinib group (n = 29)

Historical group (n = 33)

P
After induction therapy    
   CR1 (%)   23 (79.3)   27 (81.8)   .803  
   Refractory (%)   6 (20.7)   6 (18.2)   
After consolidation therapy    
   Sustained CR1 (%)   22/23 (95.7)   16/27 (59.3)   .003  
   Relapse (%)   1/23 (4.3)   11/27 (40.7)   
After salvage therapy    
   CR1 (%)   3/6 (50.0)   1/6 (16.7)   .545  
   Refractory (%)   3/6 (50.0)   5/6 (83.3)   
Pretransplantation disease status    
   CR1 (%)*  25 (86.2)  17 (51.5)   .004  
   CR2 (%)   0   9 (27.3)   
   Refractory (%)
 
4 (13.8)
 
7 (21.2)
 

 

CR1 indicates first complete remission; and CR2, second complete remission.

*

Sustained CR1 during the consolidation phase plus newly achieved CR1 after the imatinib or salvage chemotherapy

Includes 7 patients with molecular CR

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