Table 1.

MCp concentrations in the small intestine of chemokine receptor-deficient and chemokine-deficient mice and their wild-type controls


Mouse strains/wild-type control

Intestine

Spleen

Bone marrow
CCR2-/-  1758 ± 621 (2)   ND   ND  
   C57BL/6J   1819 ± 822 (2)   ND   ND  
CCR3-/-  8104 ± 2513 (3)   208 (1)   650 (1)  
   BALB/cJ   7143 ± 3830 (3)   237 (1)   917 (1)  
CCR5-/-  946 ± 246 (3)   161 (1)   412 ± 79 (2)  
   B6.129(PF2)   902 ± 336 (3)   258 (1)   529 ± 45 (2)  
MCP-1-/-  1523 (1)   ND   424 (1)  
   C57BL/6J
 
724 (1)
 
ND
 
431 (1)
 

Mouse strains/wild-type control

Intestine

Spleen

Bone marrow
CCR2-/-  1758 ± 621 (2)   ND   ND  
   C57BL/6J   1819 ± 822 (2)   ND   ND  
CCR3-/-  8104 ± 2513 (3)   208 (1)   650 (1)  
   BALB/cJ   7143 ± 3830 (3)   237 (1)   917 (1)  
CCR5-/-  946 ± 246 (3)   161 (1)   412 ± 79 (2)  
   B6.129(PF2)   902 ± 336 (3)   258 (1)   529 ± 45 (2)  
MCP-1-/-  1523 (1)   ND   424 (1)  
   C57BL/6J
 
724 (1)
 
ND
 
431 (1)
 

Values are the mean MCp concentration (± SEM for n = 3, or ½ range for n = 2) in the indicated tissue from the various mice. Deficient mice and their wild-type controls (listed directly below) were evaluated in parallel. The number of experiments is indicated in parentheses.

ND indicates not determined.