Table 3.

Impaired erythropoiesis in Pim-1-, Pim-2-, and Akt-1-deficient animals


Genotype

CFU-Es
WT   355 ± 28  
Pim-1KO  154 ± 24  
Pim-2KO  113 ± 11  
Pim-1KO/Pim-2KO  105 ± 13  
Pim-1KO/Akt-1KO  79 ± 11  
Pim-2KO/Akt-1KO  53 ± 19  
Pim-1KO/Pim-2KO/Akt-1KO
 
18 ± 8
 

Genotype

CFU-Es
WT   355 ± 28  
Pim-1KO  154 ± 24  
Pim-2KO  113 ± 11  
Pim-1KO/Pim-2KO  105 ± 13  
Pim-1KO/Akt-1KO  79 ± 11  
Pim-2KO/Akt-1KO  53 ± 19  
Pim-1KO/Pim-2KO/Akt-1KO
 
18 ± 8
 

Mean ± SD of erythroid colony-forming units (CFU-Es) (n = 3) observed after the differentiation of bone marrow cells from mice of each genotype.

See Table 1 for abbreviations.

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