Table 3. PCLP1/podocalyxin expression is... | American Society of Hematology

Table 3.

PCLP1/podocalyxin expression is reactivated by PHZ-induced hemolytic anemia, and its deficiency induces accumulation of erythrocyte precursors within the hematopoietic compartments

	Hematocrit, %	Reticulocyte index,^* %	PCLP1⁺ cells in BM, %
PBS-treated mice
Day 2	45 ± 5	2 ± 1	1 ± 1
PHZ-treated mice
Day 2†	32 ± 3	4 ± 3	11 ± 2
Day 3	23 ± 4	9 ± 3	24 ± 4
Day 6	41 ± 6	67 ± 5	19 ± 3
Day 9	52 ± 4	12 ± 2	3 ± 1

	Hematocrit, %	Reticulocyte index,^* %	PCLP1⁺ cells in BM, %
PBS-treated mice
Day 2	45 ± 5	2 ± 1	1 ± 1
PHZ-treated mice
Day 2†	32 ± 3	4 ± 3	11 ± 2
Day 3	23 ± 4	9 ± 3	24 ± 4
Day 6	41 ± 6	67 ± 5	19 ± 3
Day 9	52 ± 4	12 ± 2	3 ± 1

The results are expressed as the mean ± SD of 3 separate analyses.

Reticulocyte index is expressed as corrected reticulocyte count. Corrected reticulocyte count (%) = reticulocyte count (%) × 45 (normal hematocrit rate)

†

Twenty-four hours after second injection of PHZ

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