Longitudinal linear regression analyses of patient- and platelet-related variables affecting interval to next transfusion
Variable . | Days to next transfusion* . | 95% confidence interval . | P . |
|---|---|---|---|
| Patient related | |||
| Decrease days to next transfusion | |||
| Females with at least 2 pregnancies, or males | -0.40 | -0.21 to -0.59 | < .001 |
| DIC | -0.40 | -0.05 to -0.75 | .03 |
| Heparin | -0.37 | -0.20 to -0.56 | < .001 |
| Lymphocytotoxic antibody-positive | -0.36 | -0.19 to -0.54 | < .001 |
| Bleeding | -0.33 | -0.23 to -0.43 | < .001 |
| Amphotericin | -0.28 | -0.20 to -0.36 | < .001 |
| Fever | -0.25 | -0.18 to -0.31 | < .001 |
| Palpable spleen | -0.23 | -0.05 to -0.42 | .01 |
| Infection | -0.18 | -0.11 to -0.25 | < .001 |
| Transfusion sequence† | -0.02 | -0.02 to -0.03 | < .001 |
| Weight‡ | -0.01 | 0.00 to -0.01 | < .001 |
| Platelet related | |||
| Increase days to next transfusion | |||
| Platelets stored no more than 48 hours | 0.19 | 0.12 to 0.26 | < .001 |
| Platelet dose§ | 0.16 | 0.14 to 0.19 | < .001 |
| Decrease days to next transfusion | |||
| UVB-PC | -0.21 | -0.06 to -0.37 | .006 |
Variable . | Days to next transfusion* . | 95% confidence interval . | P . |
|---|---|---|---|
| Patient related | |||
| Decrease days to next transfusion | |||
| Females with at least 2 pregnancies, or males | -0.40 | -0.21 to -0.59 | < .001 |
| DIC | -0.40 | -0.05 to -0.75 | .03 |
| Heparin | -0.37 | -0.20 to -0.56 | < .001 |
| Lymphocytotoxic antibody-positive | -0.36 | -0.19 to -0.54 | < .001 |
| Bleeding | -0.33 | -0.23 to -0.43 | < .001 |
| Amphotericin | -0.28 | -0.20 to -0.36 | < .001 |
| Fever | -0.25 | -0.18 to -0.31 | < .001 |
| Palpable spleen | -0.23 | -0.05 to -0.42 | .01 |
| Infection | -0.18 | -0.11 to -0.25 | < .001 |
| Transfusion sequence† | -0.02 | -0.02 to -0.03 | < .001 |
| Weight‡ | -0.01 | 0.00 to -0.01 | < .001 |
| Platelet related | |||
| Increase days to next transfusion | |||
| Platelets stored no more than 48 hours | 0.19 | 0.12 to 0.26 | < .001 |
| Platelet dose§ | 0.16 | 0.14 to 0.19 | < .001 |
| Decrease days to next transfusion | |||
| UVB-PC | -0.21 | -0.06 to -0.37 | .006 |
Estimated change in days to next transfusion
An increase of 1 in the transfusion sequence number decreases the days to next transfusion by 0.02 days
An increase of 1 kg in weight decreases the days to next transfusion by 0.01 days
An increase of 1011 platelets transfused increases the days to next transfusion by 0.16 days