Table 1. Clinical data and urinary... | American Society of Hematology

Table 1.

Clinical data and urinary hepcidin levels in patients with iron overload disorders

Patient	Disease	Sex	Age, y	HCT, %	Hb, g/dL	MCV, fL	Fe, μg/dL	Ferritin, ng/mL	Hepcidin, ng/mg creatinine	Transfusions	Chelation
1	β-TI	F	24	24	7	67	120	170	4	N	N
2	β-TI	M	32	23	6	63	110	850	3	Occasional	DFO
3	β-TI	F	45	28	7.4	59	126	720	< 2	N	N
4	β-TI	M	45	29	7.5	63	110	680	9	N	N
5	β-TI	M	52	27	8	68	145	650	7	Occasional	DFO
6	β-TI	M	37	29	8.2	62	156	260	69	N	N
7	β-TI	F	44	32	9.1	65	120	180	< 2	N	N
8	β-TM	M	28	33	9.2	68	110	2600	6	Y	DFO
9	β-TM	F	23	33	9.2	65	125	4200	< 2	Y	DFO
10	β-TM	F	28	29	7.9	93	87	3200	10	Y	DFO
11	β-TM	M	29	33	9.1	78	110	1300	< 2	Y	DFO
12	β-TM	M	30	33	9.5	78	68	1250	35	Y	DFO
13	β-TM	M	36	32	9	85	120	9200	124	Y	DFO/L1
14	β-TM	M	35	30	9.5	75	-	6500	5	Y	DFO/L1
15	β-TM	F	26	32	9	82	110	3250	231	Y	DFO/L1
16	CDAI	M	42	23	6.3	115	80	1300	< 2	N	DFO
17	CDAI	F	47	26	7.2	115	145	1030	< 2	Occasional	DFO
18	ID	M	67	32	9	61.2	18	30	< 2	N	N
19	JH (HAMP)	F	32	45	15.4	88	269	64	< 2	N	N
20	JH (HAMP)	F	35	42	14.5	91	229	56	< 2	N	N
21	HH type 4	M	70	43	14	92	80.9	2352	673	N	N
22	HH type 4	M	31	36.5	12	94	49.6	1396	552	N	N

Patient	Disease	Sex	Age, y	HCT, %	Hb, g/dL	MCV, fL	Fe, μg/dL	Ferritin, ng/mL	Hepcidin, ng/mg creatinine	Transfusions	Chelation
1	β-TI	F	24	24	7	67	120	170	4	N	N
2	β-TI	M	32	23	6	63	110	850	3	Occasional	DFO
3	β-TI	F	45	28	7.4	59	126	720	< 2	N	N
4	β-TI	M	45	29	7.5	63	110	680	9	N	N
5	β-TI	M	52	27	8	68	145	650	7	Occasional	DFO
6	β-TI	M	37	29	8.2	62	156	260	69	N	N
7	β-TI	F	44	32	9.1	65	120	180	< 2	N	N
8	β-TM	M	28	33	9.2	68	110	2600	6	Y	DFO
9	β-TM	F	23	33	9.2	65	125	4200	< 2	Y	DFO
10	β-TM	F	28	29	7.9	93	87	3200	10	Y	DFO
11	β-TM	M	29	33	9.1	78	110	1300	< 2	Y	DFO
12	β-TM	M	30	33	9.5	78	68	1250	35	Y	DFO
13	β-TM	M	36	32	9	85	120	9200	124	Y	DFO/L1
14	β-TM	M	35	30	9.5	75	-	6500	5	Y	DFO/L1
15	β-TM	F	26	32	9	82	110	3250	231	Y	DFO/L1
16	CDAI	M	42	23	6.3	115	80	1300	< 2	N	DFO
17	CDAI	F	47	26	7.2	115	145	1030	< 2	Occasional	DFO
18	ID	M	67	32	9	61.2	18	30	< 2	N	N
19	JH (HAMP)	F	32	45	15.4	88	269	64	< 2	N	N
20	JH (HAMP)	F	35	42	14.5	91	229	56	< 2	N	N
21	HH type 4	M	70	43	14	92	80.9	2352	673	N	N
22	HH type 4	M	31	36.5	12	94	49.6	1396	552	N	N

β-TI indicates β-thalassemia intermedia; β-TM, β-thalassemia major; CDAI, congenital dyserythropoetic anemia type 1; ID, iron deficiency; JH (HAMP), juvenile hemochromatosis (HAMP 93delG mutations); HH type 4, hemochromatosis type 4 (Val162del); DFO, desferioxamine; and L1, deferiprone.

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