Table 1.

Genes differentially expressed in HMECs after treatment with MRP8/MRP14


Functional groups

Up-regulated

FC

Down-regulated

FC
Platelet aggregation  TSP-1  2    
Inflammation  IL-8  2  Heatshock factor 2  2  
 Gro-α (CXCL1)   2  Complement component C3  2  
 Gro-β (CXCL2)   2    
 Monocyte secretory protein  2    
 VCAM-1  2    
 ICAM-1  2    
 Manganese superoxide dismutase  3    
 Cytochrome b light-chain p22  2    
Endothelial integrity  Trad/Duet  4  Catenin α1  2  
 Ras-related rho  2  Coxsackievirus and adenovirus receptor  2  
   Cadherin (protocadherin β17)  2  
   Bullous pemphigoid antigen 1  2  
   Matrilin-2  2  
   αV-β3 integrin  2  
   Formyl peptide receptor–like 2  3  
   TGF-β2 receptor α  2  

 

 

 
Krev-1 (Rap1)
 
2
 

Functional groups

Up-regulated

FC

Down-regulated

FC
Platelet aggregation  TSP-1  2    
Inflammation  IL-8  2  Heatshock factor 2  2  
 Gro-α (CXCL1)   2  Complement component C3  2  
 Gro-β (CXCL2)   2    
 Monocyte secretory protein  2    
 VCAM-1  2    
 ICAM-1  2    
 Manganese superoxide dismutase  3    
 Cytochrome b light-chain p22  2    
Endothelial integrity  Trad/Duet  4  Catenin α1  2  
 Ras-related rho  2  Coxsackievirus and adenovirus receptor  2  
   Cadherin (protocadherin β17)  2  
   Bullous pemphigoid antigen 1  2  
   Matrilin-2  2  
   αV-β3 integrin  2  
   Formyl peptide receptor–like 2  3  
   TGF-β2 receptor α  2  

 

 

 
Krev-1 (Rap1)
 
2
 

FC indicates fold change of gene expression after treatment with MRP8/MRP14.

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