Table 6.

Multivariate analysis of freedom from progression




No. patients

Risk ratio*(95% CI)

P
CD8+ T-cell dose    
   At or above 50th percentile   31   0.2 (0.1-0.6)   .003  
   Below 50th percentile   25   1.0   NA  
Advanced disease    
   Yes   20   0.4 (0.2-1.0)   .06  
   No   36   1.0   NA  
Chronic GVHD, extensive    
   Yes   20   0.3 (0.1-1.2)   .09  
   No
 
36
 
1.0
 
NA
 



No. patients

Risk ratio*(95% CI)

P
CD8+ T-cell dose    
   At or above 50th percentile   31   0.2 (0.1-0.6)   .003  
   Below 50th percentile   25   1.0   NA  
Advanced disease    
   Yes   20   0.4 (0.2-1.0)   .06  
   No   36   1.0   NA  
Chronic GVHD, extensive    
   Yes   20   0.3 (0.1-1.2)   .09  
   No
 
36
 
1.0
 
NA
 

Patients not evaluable for chronic graft-versus-host disease were excluded from analysis for both covariates. NA indicates not applicable.

GVHD indicates graft-versus-host disease.

*

Risk ratio value indicates likelihood of death and/or disease progression (progression-free survival) with, respectively, indicated CD8+ T-cell dose or presence of chronic graft-versus-host disease

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