G-PBMC graft cell dose
Cell dose . | Sibling donor, median (range)* . | Unrelated donor, median (range)* . | P . |
|---|---|---|---|
| Total nucleated cell, × 108/kg | 14.0 (5.7-26.5) | 10.0 (3.3-18.1) | < .001 |
| CD34+ cell, × 106/kg | 7.3 (2.3-17.7) | 7.4 (1.9-16.8) | .72 |
| T-cell subsets | |||
| CD3+ T-cell, × 108/kg | 3.5 (2.0-6.0) | 2.6 (0.8-6.4) | < .001 |
| CD4+ T-cell, × 108/kg | 2.4 (1.1-4.1) | 1.5 (0.4-2.5) | < .001 |
| CD8+ T-cell, × 108/kg | 1.1 (0.5-2.6) | 0.9 (0.2-3.4) | .10 |
Cell dose . | Sibling donor, median (range)* . | Unrelated donor, median (range)* . | P . |
|---|---|---|---|
| Total nucleated cell, × 108/kg | 14.0 (5.7-26.5) | 10.0 (3.3-18.1) | < .001 |
| CD34+ cell, × 106/kg | 7.3 (2.3-17.7) | 7.4 (1.9-16.8) | .72 |
| T-cell subsets | |||
| CD3+ T-cell, × 108/kg | 3.5 (2.0-6.0) | 2.6 (0.8-6.4) | < .001 |
| CD4+ T-cell, × 108/kg | 2.4 (1.1-4.1) | 1.5 (0.4-2.5) | < .001 |
| CD8+ T-cell, × 108/kg | 1.1 (0.5-2.6) | 0.9 (0.2-3.4) | .10 |
G-PBMC indicates granulocyte colony-stimulating factor-mobilized peripheral blood mononuclear cells; kg, kilogram. For sibling donors, n = 38; for unrelated donors, n = 25.
For the entire patient group (n = 63), the median absolute cell numbers per kilogram of recipient body weight were as follows: total nucleated cell, 12.0 × 108/kg (range, 3.3-26.5 × 108/kg); CD34+ cell, 7.4 × 106/kg (range, 1.9-17.7 × 106/kg); CD3+ T-cell, 3.2 × 108/kg (range, 0.8-6.4 × 108/kg); CD4+ T-cell, 2.1 × 108/kg (range, 0.4-4.1 × 108/kg); and CD8+ T-cell, 1.1 × 108/kg (range, 0.2-3.4 × 108/kg)