Table 2. Algorithm used to find probe... | American Society of Hematology

Table 2.

Algorithm used to find probe sets with differential expression in PD and CR patients

	1st comparison	2nd comparison	Cross-comparison
Compared groups of patients	3 PD^* vs 10 CR†	5 PD‡ vs 3 CR§	3 PD^* vs 3 CR§ + 10 PD† vs 3 CR‡
Comparison files	3 × 10 = 30	5 × 3 = 15	10 × 5 + 3 × 3 = 59
Comparison files with probe sets altered (%)	21/30 (70)	10/15 (67)	41/59 (69)
Change algorithm: probe sets decreased	51	338	62
Signal log ratio algorithm: probe sets of – 1 or less	217	617	109
Probe sets selected by both algorithms	28	207	35
Probe sets selected by 1st and 2nd comparison	16	16	10∥

	1st comparison	2nd comparison	Cross-comparison
Compared groups of patients	3 PD^* vs 10 CR†	5 PD‡ vs 3 CR§	3 PD^* vs 3 CR§ + 10 PD† vs 3 CR‡
Comparison files	3 × 10 = 30	5 × 3 = 15	10 × 5 + 3 × 3 = 59
Comparison files with probe sets altered (%)	21/30 (70)	10/15 (67)	41/59 (69)
Change algorithm: probe sets decreased	51	338	62
Signal log ratio algorithm: probe sets of – 1 or less	217	617	109
Probe sets selected by both algorithms	28	207	35
Probe sets selected by 1st and 2nd comparison	16	16	10∥

Patient numbers 8, 11, 14

Patient numbers 13, 25, 30, 33, 35, 38, 50, 51, 54, 55

Patient numbers 2, 7, 9, 10, 19

Patient numbers 45, 48, 56

Probe sets common in 1st, 2nd, and cross-comparison