Table 5. Virologic and immunologic... | American Society of Hematology

Table 5.

Virologic and immunologic responses to CTL infusion

	EBV load (cp/μg DNA) in PBMCs					LMP2-specific T cells (SFCs/1 × 10⁶ PBMCs)
Patient no.	Before	2 wk after	6 wk after	Epitope tested	Before	2 wk after	6 wk after	Epitope tested	Before	2 wk after	6 wk after
729	10	46	0	FLY	8	26	15^*	NLV	2623	2521	1896^*
606	295	114	324	IED	9	5	50	NLV	995	958	1181
				LIV	4	ND	26
697	31	193	519	FLY	14	0	9	NLV	144	143	96
815	367	174	147	ND				ND
845	797	286	103	ND				ND
894	0	0	0	RRL‡	11	44	3†	ND
389	347	120	156	CLG	16	10	18	NLV	114	100	95
918	87	27	0	SSC	15	63	20	ND
1042	664	120	367	TVC	116	171	84	NLV	2510	2960	2596
1046	67	56	54	FTA‡	0	0	0	ND

	EBV load (cp/μg DNA) in PBMCs					LMP2-specific T cells (SFCs/1 × 10⁶ PBMCs)
Patient no.	Before	2 wk after	6 wk after	Epitope tested	Before	2 wk after	6 wk after	Epitope tested	Before	2 wk after	6 wk after
729	10	46	0	FLY	8	26	15^*	NLV	2623	2521	1896^*
606	295	114	324	IED	9	5	50	NLV	995	958	1181
				LIV	4	ND	26
697	31	193	519	FLY	14	0	9	NLV	144	143	96
815	367	174	147	ND				ND
845	797	286	103	ND				ND
894	0	0	0	RRL‡	11	44	3†	ND
389	347	120	156	CLG	16	10	18	NLV	114	100	95
918	87	27	0	SSC	15	63	20	ND
1042	664	120	367	TVC	116	171	84	NLV	2510	2960	2596
1046	67	56	54	FTA‡	0	0	0	ND

cp indicates copies; wk, weeks; ND, not done as not enough PBMCs or no informative peptide was available.

At 3 months after CTLs, as a sufficient number of PBMCs was not available at 6 weeks after CTLs time point.

At 8 weeks after CTLs, as a sufficient number of PBMCs was not available at 6 weeks after CTLs time point.

Pentadecamers containing minimum epitope were used for stimulation.